Prevalence and correlates of hyperglycemia in a rural population, Vietnam: implications from a cross–sectional study

BMC Public Health

Duong Van Thanh¹  Tran Khanh Long²  Pham Van Thang³  Dang Dinh Thoang³  Bui Thi Nhung⁴  Pham Tran Phuong¹  Tran Quang Binh¹ 

[1] Department of Immunology and Molecular Biology, National Institute of Hygiene and Epidemiology, 1 Yersin, Hanoi, Vietnam;Hanoi School of Public Health, 138 Giang Vo Street, Hanoi, Vietnam;Ha Nam Center for Preventive Medicine, Truong Chinh Street, Phu Ly City, Vietnam;National Institute of Nutrition, 48B Tang Bat Ho Street, Hanoi, Vietnam

关键词: Vietnamese;    Risk factors;    Prevalence;    Population–based study;    Type 2 diabetes;   

Others  :  1162892
DOI  :  10.1186/1471-2458-12-939

 received in 2012-08-09, accepted in 2012-10-29,  发布年份 2012

【 摘 要 】

Background

Despite the increasing prevalence of type 2 diabetes in urban areas, relatively little has been known about its actual prevalence and its associations in rural areas, Vietnam. The purpose of this study was to evaluate the prevalence of impaired fasting glucose (IFG), impaired glucose tolerance (IGT), diabetes and their risk factors in a rural province, Vietnam.

Methods

A cross–sectional study with a representative sample was designed to estimate the hyperglycemia prevalence, using 75–g oral glucose tolerance test. Potential risk factors for hyperglycemia were analyzed using multinomial logistic regression, taken into account influences of socio–economic status, anthropometric measures, and lifestyle–related factors.

Results

The age and sex–adjusted prevalence rates (95% CI) of isolated IFG, isolated IGT, combined IFG–IGT, and diabetes were 8.7 (7.0–10.5), 4.3 (3.2−5.4), 1.6 (0.9−2.3), and 3.7% (2.7–4.7%), respectively. There were still 73% of diabetic subjects without knowing the condition. Blood pressure, family history of diabetes, obesity–related measures (waist circumference, waist–hip ratio, body fat percentage, and abdominal obesity) were the independent risk factors for hyperglycemia (IFG, IGT, and diabetes).

Conclusions

The prevalence of hyperglycemia in rural areas has not been as sharply increased as that reported in urban cities, Vietnam. Blood pressure and obesity–related measures were the most significant predictors for hyperglycemia level and they can be taken into account in building prognosis models to early detection of diabetes in rural Vietnamese populations.

【 授权许可】

   
2012 Quang Binh et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Shaw JE, Sicree RA, Zimmet PZ: Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010, 87:4-14.
• [2]Quoc PS, Charles MA, Cuong NH, Lieu LH, Tuan NA, Thomas M, Balkau B, Simon D: Blood glucose distribution and prevalence of diabetes in Hanoi (Vietnam). Am J Epidemiol 1994, 139:713-722.
• [3]Binh VT, Uoc KH: Epidemiology of diabetes in Vietnam: Treatment methods and preventive measures. Hanoi: Medical Publisher; 2005.
• [4]Trach MT, Toan DTB, Binh DTT, Thang HQ, et al.: Basic epidemiology survey on diabetes mellitus in urban areas of Ho Chi Minh City. Pharmaceutical and Medical Magazine of Ho Chi Minh City 1994, 2:171-174.
• [5]Son LNTD, Kusama K, Hung NTK, Loan TTH, Chuyen NV, Kunii D, Sakai T, Yamamoto S: Prevalence and risk factors for Diabetes in Ho Chi Minh City, Vietnam. Diabetic Med 2004, 21:371-376.
• [6]Ta MT, Nguyen KT, Nguyen ND, Campbell LV, Nguyen TV: Identification of undiagnosed type 2 diabetes by systolic blood pressure and waist–to–hip ratio. Diabetologia 2010, 53:2139-2146.
• [7]Khoi HH: Problems of nutrition in transition period. Problems of Nutrition in Transition Period in Vietnam. Hanoi: Medical Publishing House; 1996:153-226.
• [8]General Statistics Office: The 2009 Vietnam Population and Housing Census: Completed results. Hanoi: Statistical Publishing House; 2012. Available from www.gso.gov.vn webcite
• [9]World Health Organization: Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: Report of a WHO consultation. Geneva: World Health Organization; 2006.
• [10]WHO Expert Consultation: Appropriate body–mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004, 363:157-163.
• [11]International Obesity Task Force (on behalf of the Steering Committee): The Asia–Pacific Perspective: Redefining obesity and its treatment. Sydney: Western Pacific Region. Health Communications Australia; 2002.
• [12]Jonas JB, Panda Jonas S: Diabetes mellitus in rural India. Epidemiology 2010, 21:754-755.
• [13]Zhang YH, Ma WJ, Thomas GN, Xu YJ, Lao XQ, Xu XJ, Song XL, Xu HF, Cai QM, Xia L, Nie SP, Deng HH, Yu IT: Diabetes and pre–diabetes as determined by glycated haemoglobin a1c and glucose levels in a developing southern Chinese population. PLoS One 2012, 7:e37260.
• [14]Aekplakorn W, Chariyalertsak S, Kessomboon P, Sangthong R, Inthawong R, Putwatana P, Taneepanichskul S, Thai National Health Examination Survey IV Study Group: Prevalence and management of diabetes and metabolic risk factors in Thai adults: the Thai National Health Examination Survey IV, 2009. Diabetes Care 2011, 34:1980-1985.
• [15]Sekikawa A, Eguchi H, Tominaga M, Igarashi K, Abe T, Manaka H, Sasaki H, Fukuyama H, Kato T, Kiyohara Y, Fujishima M: Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in a rural area of Japan: the Funagata Diabetes Study. J Diabetes Complications 2006, 14:78-83.
• [16]Kim DJ: The epidemiology of diabetes in Korea. Diabetes Metab J 2011, 35:303-308.
• [17]Popkin BM, Horton SH, Kim S: The Nutrition Transition and Prevention of Diet–Related Diseases in Asia and Pacific. Food Nutri Bullet 2001, 22:1-58.
• [18]James C, Bullard KM, Rolka DB, Geiss LS, Williams DE, Cowie CC, Albright A, Gregg EW: Implications of alternative definitions of prediabetes for prevalence in U.S. adults. Diabetes Care 2011, 34:387-391.
• [19]Zhang YH, Ma WJ, Thomas GN, Xu YJ, Lao XQ, et al.: Diabetes and prediabetes as determined by glycated haemoglobin A1c and glucose levels in a developing southern Chinese population. PLoS One 2012, 7:e37260.
• [20]Tabák AG, Herder C, Rathmann W, Brunner EJ, Kivimäki M: Prediabetes: a high-risk state for diabetes development. Lancet 2012, 379:2279-2290.
• [21]Govindarajan G, Sowers JR, Stump CS: Hypertension and diabetes mellitus. European Cardiology 2006, 2:1-7.
• [22]Roccella EJ, Sowers JR, Cutler JA, Donato K, Eastman RC, Falkner B, Horan MJ, Hsueh WA, Hyman B, Reed JW, Savage PJ, Siwek J, Tuck ML, Weinberger MH, Williams G: National High Blood Pressure Education Program Working Group report on hypertension in diabetes. Hypertension 1994, 23:145-158.
• [23]Mullican DR, Lorenzo C, Haffner SM: Is prehypertension a risk factor for the development of Type2 diabetes? Diabetes Care 2009, 32:1870-1872.
• [24]Conen D, Ridker PM, Mora S, Buring JE, Glynn RJ: Blood pressure and risk of developing type 2 diabetes mellitus: the Women’s Health Study. Eur Heart J 2007, 28:2937-2943.
• [25]Cruickshank K, Riste L, Anderson SG, Wright JS, Dunn G, Gosling RG: Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 2002, 106:2085-2090.
• [26]Dokken BB: The pathophysiology of cardiovascular disease and diabetes: beyond blood pressure and lipids. Diabetes Spectrum 2008, 21:160-165.
• [27]American Diabetes Association: Diagnosis and classification of diabetes mellitus. Diabetes Care 2005, 28:S37-S42.
• [28]Chan JC, Malik V, Jia W, Kadowaki T, Yajnik CS, Yoon KH, Hu FB: Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA 2009, 301:2129-2140.
• [29]Weber MB, Oza Frank R, Staimez LR, Ali MK, Narayan KM: Type 2 Diabetes in Asians: Prevalence, Risk Factors, and Effectiveness of Behavioral Intervention at Individual and Population Levels. Annu Rev Nutr 2012.
• [30]Kim SM, Lee JS, Lee J, Na JK, Han JH, Yoon DK, Baik SH, Choi DS, Choi KM: Prevalence of diabetes and impaired fasting glucose in Korea: Korean National Health and Nutrition Survey 2001. Diabetes Care 2006, 29:226-231.
• [31]Liu C, Yu Z, Li H, Wang J, Sun L, Qi Q, Lin X: Associations of alcohol consumption with diabetes mellitus and impaired fasting glycemia among middle-aged and elderly Chinese. BMC Publ Health 2010, 10:713. BioMed Central Full Text
• [32]Nakanishi N, Suzuki K, Tatara K: Alcohol consumption and risk for development of impaired fasting glucose or type 2 diabetes in middle-aged Japanese men. Diabetes Care 2003, 26:48-54.
• [33]Parry CD, Patra J, Rehm J: Alcohol consumption and non-communicable diseases: epidemiology and policy implications. Addiction 2011, 106:1718-1724.
• [34]Stahl M, Jorgensen LG, Hyltoft PP, Brandslund I, de Fine Olivarius N, Borch-Johnsen K: Optimization of preanalytical conditions and analysis of plasma glucose. 1. Impact of the new WHO and ADA recommendations on diagnosis of diabetes mellitus. Scand J Clin Lab Invest 2001, 61:169-179.