High prevalence of previous dengue virus infection among first-generation Surinamese immigrants in the Netherlands

BMC Infectious Diseases

Gerard JB Sonder³  Janke Schinkel²  Anneke van den Hoek³  Femke W Overbosch¹ 

[1] National Coordination Centre for Traveller’s Health Advice (LCR), Amsterdam, The Netherlands;Department of Medical Microbiology, Section of Clinical Virology, Academic Medical Center, Amsterdam, The Netherlands;Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, The Netherlands

关键词: Immigrants;    VFRs;    Travellers;    Americas;    Suriname;    Prevalence;    Seroprevalence;    DENV;    Dengue virus infection;    Dengue;   

Others  :  1125592
DOI  :  10.1186/1471-2334-14-493

 received in 2014-01-08, accepted in 2014-09-02,  发布年份 2014

【 摘 要 】

Background

A substantial portion of Dutch travellers is comprised of immigrants returning to their country of origin to visit friends and relatives (VFRs), including VFRs returning to dengue-endemic areas such as Suriname. Limited attention has been focused on dengue among immigrants, therefore it is unknown whether immigration has effect on the epidemiology of (severe) dengue among VFRs.

To get more insight in the seroprevalence of dengue among Surinamese immigrants, we conducted a seroprevalence study on a convenience sample of first-generation Surinamese immigrants living in the Netherlands.

Methods

Blood samples were tested for IgG antibodies to DENV antigen serotypes (1, 2, 3 and 4). Gender, age, years lived in Suriname before immigration, history of yellow fever vaccination, and time between yellow fever vaccination and blood sample collection were examined as possible predictors for previous infection.

Results

Of the studied 400 Surinamese travellers with a mean age of 52 years (range 18–89), 37% were male. Serology suggestive of past DENV infection was found in 325 individuals (81.3%; 95% CI: 77-85%). The time lived in Suriname before immigration was the only significant predictor for previous DENV infection.

Conclusions

Most first-generation Surinamese immigrants have evidence of past DENV infection, probably comparable to Surinamese inhabitants. Whether this influences the number of cases of (severe) dengue when travelling requires more study.

【 授权许可】

   
2014 Overbosch et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]World Health Organization: Dengue and severe dengue. Factsheet N° 117, January 2012. [Available: http://www.who.int/mediacentre/factsheets/fs117/en/ webcite. Accessed 30 August, 2012]
• [2]Kouri GP, Guzmán MG, Bravo JR, Triana C: Dengue haemorrhagic fever/dengue shock syndrome: lessons from the Cuban epidemic, 1981. Bull World Health Organ 1989, 67(4):375-380.
• [3]Burke DS, Nisalak A, Johnson DE, Scott RM: A prospective study of dengue infections in Bangkok. Am J Trop Med Hyg 1988, 38(1):172-180.
• [4]Baaten GGG, Sonder GJB, Zaaijer HL, van Gool T, Kint JAPCM, van den Hoek A: Travel-related dengue virus infection, the Netherlands, 2006–2007. Emerg Infect Dis 2011, 17(5):821-828.
• [5]Overheid Republiek Suriname: Over Suriname, demografie. [Available: http://www.gov.sr/sr/over-suriname/demografie.aspx webcite. Accessed 23 January, 2013]. (In Dutch)
• [6]Algemeen Bureau voor de Statistiek in Suriname: Aangekomen en vertrokken personen. [Available: http://www.statistics-suriname.org/index.php/statistieken/database/147-aangekomen-en-vertrokken-personen webcite. Accessed 29 January, 2013]. (In Dutch)
• [7]Allicock OM, Lemey P, Tatem AJ, Pybus OG, Bennett SN, Mueller BA, Suchard MA, Foster JE, Rambaut A, Carrington CVF: Phylogeography and population dynamics of dengue virus in the Americas. Mol Biol Evol 2012, 29(6):1533-1543.
• [8]Nisalak A, Endy TP, Nimmannitya S, Kalayanarooy S, Thisayakorn U, Scott RM, Burke DS, Hoke CH, Innis BL, Vaughn DW: Serotype-specific dengue virus circulation and dengue disease in Bangkok, Thailand from 1973–1999. Am J Trop Med Hyg 2003, 68(2):191-202.
• [9]Deddens JA, Petersen MR: Approaches for estimating prevalence ratios. Occup Environ Med 2008, 65:501-506.
• [10]Rodriguez-Barraquer I, Cordeiro MT, Braga C, de Souza WV, Marques ET, Cummings DAT: From re-emergence to hyperendemicity: the natural history of the dengue epidemic in Brazil. PLoS Negl Trop Dis 2011, 5(1):e935.
• [11]Morrison AC, Minnick SL, Rocha C, Forshey BM, Stoddard ST, Getis A, Focks DA, Russell KL, Olsen JG, Blair PJ, Watts DM, Sihuincha M, Scott TW, Kochel TJ: Epidemiology of dengue virus in Iquitos, Peru 1999 to 2005: interepidemic and epidemic patterns of transmission. PLoS Negl Trop Dis 2010, 4(5):e670.
• [12]Brown MG, Vickers IE, Salas RA, Smikle MF: Seroprevalence of dengue virus antibodies in healthy Jamaicans. Hum Antibodies 2009, 18:123-126.
• [13]Yamashiro T, Disla M, Petit A, Taveras D, Castro-Bello M, Lora-Orste M, Vardez S, Cesin AJ, Garcia B, Nishizono A: Seroprevalence of IgG specific for dengue virus among adults and children in Santo Domingo, Dominican Republic. Am J Trop Med Hyg 2004, 71(2):138-143.
• [14]Balmaseda A, Standish K, Mercado JC, Matute JC, Tellez Y, Saborío S, Hammond SN, Nuñez A, Avilés W, Henn MR, Holmes EC, Gordon A, Coloma J, Kuan G, Harris E: Trends in patterns of dengue transmission over 4 years in a pediatric cohort study in Nicaragua. J Infect Dis 2010, 201(1):5-14.
• [15]San Martin JL, Brathwaite O, Zambrano B, Solórzano JO, Bouckenooghe A, Dayan GH, Guzmán MG: The epidemiology of dengue in the Americas over the last three decades: a worrisome reality. Am J Trop Med Hyg 2010, 82(1):128-135.
• [16]Pan American Health Organization: Dengue regional information: Number of cases, Data table 1995–2010. [Available: http://www.paho.org/hq/index.php?option=com_topics&view=article&id=1&Itemid=40734&lang=en webcite. Accessed September 16, 2014]
• [17]Laughlin CA, Morens DM, Cassetti MC, Costero-Saint Denis A, San Martin J, Whitehead SS, Fauci AS: Dengue research opportunities in the Americas. J Infect Dis 2012, 206(7):1121-1127.
• [18]Oudhof K, Harmsen C, Loozen S, Choenn C: Omvang en spreiding van Surinaamse bevolkingsgroepen in Nederland. [Available: http://www.cbs.nl/NR/rdonlyres/E77E4C63-775E-4708-B347-1D1DA392B119/0/2011k2b15p97art.pdf webcite. Accessed 23 January, 2013]. (In Dutch)
• [19]Guzman MG, Halstead SB, Artsob H, Buchy P, Farrar J, Gubler DJ, Hunsperger E, Kroeger A, Margolis HS, Martínez E, Nathan MB, Pelegrino JL, Simmons C, Yoksan S, Peeling RW: Dengue: a continuing global threat. Nat Rev Microbiol 2010, 8(12 Suppl):S7-16.