Alterations in circadian/seasonal rhythms and vegetative functions are related to suicidality in DSM-5 PTSD

BMC Psychiatry

Claudia Carmassi²  Valdo Ricca³  Mauro Giovanni Carta¹  Carlo Antonio Bertelloni²  Ciro Conversano²  Gabriele Massimetti²  Liliana Dell’Osso² 

[1] Department of Public Health, University of Cagliari, Cagliari, Italy;Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, Pisa 56126, Italy;Department of Neuropsychiatry, University of Florence, Florence, Italy

关键词: Vegetative functions;    Suicidal ideation;    Suicide attempts;    PTSD;    Rhythmicity;   

Others  :  1091338
DOI  :  10.1186/s12888-014-0352-2

 received in 2014-08-10, accepted in 2014-11-25,  发布年份 2014

【 摘 要 】

Background

Alterations in rhythmicity and vegetative functions have been reported as correlates of suicidality, particularly in patients with mood disorders. No investigation has addressed their impact on patients with post-traumatic stress disorder (PTSD). Aim of the present study was to fulfill this gap.

Methods

Sixty-five out- and inpatients with DSM-5 PTSD were assessed by using the Mood Spectrum-Self Report-Lifetime Version (MOODS-SR), a questionnaire for lifetime mood spectrum symptomatology including alterations in circadian/seasonal rhythms and vegetative functions. Six items of the MOODS-SR were combined and dichotomized to assess suicidal ideation and/or attempts.

Results

Significant and positive associations were found between symptoms of lifetime dysregulations in rhythmicity and vegetative functions and suicidal ideation and/or attempts. All MOODS-SR sub-domains (rhythmicity, sleep, appetite/weight, sexual function, physical symptoms) were associated with an increased likelihood of suicidal ideation, but only changes in appetite/weight were associated with greater odd ratios of suicide attempts (OR = 2.099, 95% CI 1.148-3.841).

Conclusions

Our results suggest that lifetime dysregulations in rhythmicity and vegetative functions may represent correlates of suicidality in patients with DSM-5 PTSD.

【 授权许可】

   
2014 Dell'Osso et al.; licensee BioMed Central.

【 图 表 】

Figure 1.

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