Musculoskeletal pain is associated with restless legs syndrome in young adults

BMC Musculoskeletal Disorders

David Champion⁵  Nigel McArdle²  Peter R. Eastwood²  Leon M. Straker¹  Peter B. O’Sullivan¹  Darren J. Beales¹  Anne J. Smith¹  Markus V. Paananen⁴  Stijn J. Hoogwout³ 

[1] School of Physiotherapy and Exercise Science, Curtin University, Perth 6845, Western Australia, Australia;Centre for Sleep Science, School of Anatomy, Physiology & Human Biology, University of Western Australia, 35 Stirling Highway, Crawley 6009, WA, Australia;Offenbachlaan 14, Voorschoten, 2253 CR, The Netherlands;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, FI-90014, Finland;University of New South Wales, UNSW, Sydney 2052, NSW, Australia

关键词: Sleep disorders;    Restless legs syndrome;    Musculoskeletal pain;   

Others  :  1232857
DOI  :  10.1186/s12891-015-0765-1

 received in 2015-05-16, accepted in 2015-10-08,  发布年份 2015

【 摘 要 】

Background

In recent years, there is considerable evidence of a relationship between the sensorimotor disorder restless legs syndrome (RLS) and pain disorders, including migraine and fibromyalgia. An association between multi-site pain and RLS has been reported in adult women. In the current study, we explored the association between musculoskeletal (MSK) pain and RLS in a large cohort of young adults.

Methods

Twenty two year olds (n = 1072), followed since birth of part of the Western Australian Pregnancy Cohort (Raine) Study, provided data on MSK pain (duration, severity, frequency, number of pain sites). RLS was considered present when 4 diagnostic criteria recommended by the International Restless Legs Syndrome Study Group were met (urge to move, dysaesthesia, relief by movement, worsening symptoms during the evening/night) and participants had these symptoms at least 5 times per month. Associations between MSK pain and RLS were analyzed by multivariable logistic regression with bias-corrected bootstrapped confidence intervals, with final models adjusted for sex, psychological distress and sleep quality.

Results

The prevalence of RLS was 3.0 % and MSK pain was reported by 37.4 % of the participants. In multivariable logistic regression models, strong associations were found between RLS-diagnosis and long duration (three months or more) of MSK pain (odds ratio 3.6, 95 % confidence interval 1.4–9.2) and reporting three or more pain sites (4.9, 1.6–14.6).

Conclusions

Different dimensions of MSK pain were associated with RLS in young adults, suggestive of shared pathophysiological mechanisms. Overlap between these conditions requires more clinical and research attention.

【 授权许可】

   
2015 Hoogwout et al.

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