Seroprevalence of Helicobacter pylori infection and its related risk factors in symptomatic patients in southern Ethiopia

BMC Research Notes

Techalew Shimelis¹  Demo Yemane¹  Deresse Daka¹  Endale Tadesse¹ 

[1] Department of Medical Laboratory Science, College of Medicine and Health Sciences, Hawassa University, P.O. Box 1560, Hawassa, Ethiopia

关键词: Seroprevalence;    ABO blood groups;    Helicobacter pylori;   

Others  :  1118285
DOI  :  10.1186/1756-0500-7-834

 received in 2014-06-12, accepted in 2014-11-18,  发布年份 2014

【 摘 要 】

Background

Helicobacter pylori is the main etiology of peptic ulcers and chronic gastritis. Various studies showed that blood type ‘O’ is more common among patients with peptic ulcer. The aim of this study was to determine the seroprevalence of H. pylori antibodies and its relationship with ABO/Rhesus blood groups, age, sex and residence of symptomatic patients in southern Ethiopia.

Methods

A cross-sectional study was conducted in a total of 408 consecutive patients with upper abdominal complaints at Hawassa University Hospital from October 2012 to January 2013. Data on demographic factors was collected from all participants using questionnaires. Blood samples were also collected and tested for ABO and Rh blood group phenotype using hemagglutination test and for anti-H. pylori antibody (IgG) using two different ELISAs..

Results

The overall seroprevalence of H. pylori infection was 83.3% (340/408), and it was significantly higher in rural (71.2%) compared to urban residents (28.8%) (p = 0.008). Participants with blood group AB, A, O, B, and Rh positive had H. pylori prevalence of 88.9, 84.2, 83.7, 80.9, and 83.5%, respectively. H. pylori infection was not significantly influenced by age, sex, occupation, educational status and ABO/ Rh status (p >0.05).

Conclusion

The high seroprevalence of H. pylori infection especially among rural residents calls for immediate intervention measures so that its clinical consequences could be minimized. ABO/Rh blood group was not found to be associated with H. pylori infection.

【 授权许可】

   
2014 Tadesse et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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