Small-diameter titanium grade IV and titanium-zirconium implants in edentulous mandibles: five-year results from a double-blind, randomized controlled trial

BMC Oral Health

Martin Schimmel⁷  Renzo Bassetti⁵  Jose Castro-Laza²  Stefan Hicklin⁷  Marc Quirynen³  Stefano Storelli⁴  Bilal Al-Nawas¹  Frauke Müller⁶ 

[1] Johannes-Gutenberg University Mainz, Mainz, Germany;University of Regensburg Clinic, Regensburg, Germany;School of Dentistry, Catholic University Leuven, Leuven, Belgium;University of Milan, Dental Clinic, San Paolo Hospital, Milan, Italy;Cantonal Hospital Lucerne, Clinic for Oral and Maxillofacial Surgery, Lucerne, Switzerland;Division of Gerodontology and Removable Prosthodontics, University of Geneva, Geneva, Switzerland;University of Bern, School of Dental Medicine, Bern, Switzerland

关键词: Roxolid;    Split-mouth;    SLActive;    Ti Grade IV;    TiZr;    Overdentures;   

Others  :  1228338
DOI  :  10.1186/s12903-015-0107-6

 received in 2015-05-17, accepted in 2015-10-05,  发布年份 2015

【 摘 要 】

Background

The aim of this study was to compare the 5-year survival and success rates of 3.3 mm dental implants either made from titanium-zirconium (TiZr) alloy or from Grade IV titanium (Ti Grade IV) in mandibular implant-based removable overdentures.

Methods

The core study had a follow-up period of 36 months and was designed as a randomized, controlled, double-blind, split-mouth multicenter clinical trial. Patients with edentulous mandibles received two Straumann Bone Level implants (diameter 3.3 mm, SLActive®), one of TiZr (test) and one of Ti Grade IV (control), in the interforaminal region. This follow-up study recruited patients from the core study and evaluated the plaque and sulcus bleeding indices, radiographic crestal bone level, as well as implant survival and success 60 months after implant placement.

Results

Of the 91 patients who initially received implants, 75 completed the 36 month follow-up and 49 were available for the 60 month examination. Two patients were excluded so that a total of 47 patients with an average age of 72 ± 8 years were analysed. The characteristics and 36-month performance of the present study cohort did not differ from the non-included initial participants (p > 0.05). In the period since the 36-month follow-up examination, no implant was lost. The cumulative implant survival rate was 98.9 % for the TiZr group and 97.8 % for the Ti Grade IV group. Crestal bone level changes at 60 months were not different in the test and control group (TiZr −0.60 ± 0.69 mm and Ti Grade IV −0.61 ± 0.83 mm; p = 0.96). The cumulative implant success rate after 60 months was 95.8 and 92.6 % for TiZr and Ti Grade IV, respectively.

Conclusions

After 60 months, the positive outcomes of the 36 month results for TiZr and Ti Grade IV implants were confirmed, with no significant differences with regard to crestal bone level change, clinical parameters and survival or success rates. TiZr implants performed equally well compared to conventional Ti Grade IV 3.3 mm diameter-reduced implants for mandibular removable overdentures.

Trial registration

Registered on www.clinicaltrials.gov:NCT01878331

【 授权许可】

   
2015 Müller et al.

【 图 表 】

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