Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults

BMC Public Health

Jose R Fernandez²  Jamy D Ard⁴  April P Carson⁵  Virginia J Howard⁵  Suzanne E Judd³  Akilah Dulin Keita¹ 

[1] Institute for Community Health Promotion, Brown University, Box G-S121-8, Providence, USA;Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Blvd., Webb 449A Birmingham AL 35205, USA;Department of Biostatistics, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham AL 35205, USA;Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, USA;Department of Epidemiology, University of Alabama at Birmingham, Ryals 210 F, 1530 3rd Avenue South, Birmingham AL 35205, USA

关键词: Cardiovascular disease;    Metabolic syndrome;    Socioeconomic factors;    Neighborhoods;   

Others  :  1091302
DOI  :  10.1186/1471-2458-14-1319

 received in 2014-07-29, accepted in 2014-12-17,  发布年份 2014

【 摘 要 】

Background

The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation.

Methods

The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS.

Results

Among black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity (p < .01), lower HDL (p < .001), high blood pressure (p < .01), elevated fasting glucose (p < .001), inflammation (p < .01), and CRP-MetS (p < .001). Among white adults, neighborhood deprivation was associated with higher waist circumference (p < .001), lower HDL (p < .001), higher triglycerides (p < .01), higher glucose (p < .001), higher BMI (p < .0001), higher blood pressure (p = .01), METS (p < .001), inflammation (p < .01) and CRP-MetS (p < .001).

Conclusions

These findings highlight the role of neighborhood socioeconomic deprivation on METS and CRP-MetS for black and white adults. Interventions tailored to address the contextual effects of deprived neighborhoods may reduce the observed neighborhood disparities.

【 授权许可】

   
2014 Keita et al.; licensee BioMed Central.

【 图 表 】

Figure 1.

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