期刊论文详细信息
BMC Public Health
Tuberculosis case finding and isoniazid preventive therapy among people living with HIV at public health facilities of Addis Ababa, Ethiopia: a cross-sectional facility based study
Bethabile Lovely Dolamo2  Amenu Wesen Denegetu1 
[1] DLitt et Phil in Health Studies from University of South Africa, STOP Consultant, WHO/South Sudan, P.O. Box: 22751, Addis Ababa, Ethiopia;Department of Health Studies, University of South Africa, P.O. Box 392 UNISA, 0003, Pretoria, South Africa
关键词: Tuberculosis;    Screening;    PLHIV;    INH preventive therapy;    HIV;   
Others  :  1161331
DOI  :  10.1186/1471-2458-14-52
 received in 2013-07-12, accepted in 2014-01-15,  发布年份 2014
PDF
【 摘 要 】

Background

Activities to decrease the burden of tuberculosis (TB) among people living with HIV (PLHIV) include intensified TB case-finding (ICF), Isoniaizid (INH) preventive therapy (IPT) and infection control in health-care and congregate settings (IC). Information about the status of collaborative TB/HIV care services which decreases the burden of TB among PLHIV in Ethiopia is limited. The purpose of the study was to assess TB case finding and provision of IPT among PLHIV in Addis Ababa.

Methods

A cross sectional, facility-based survey was conducted between June 2011 and August 2011. Data was collected by interviewing 849 PLHIV from ten health facilities in Addis Ababa. Both descriptive and inferential statistics were used to analyze findings and the results are described in this report.

Results

The proportion of PLHIV who have been screened for TB during any one of their follow-up cares was 92.8%. Eighty eight (10.4%) of the study participants have been diagnosed for TB during their HIV follow-up cares. PLHIV who had never been diagnosed for TB before they knew their positive HIV status were nearly four times more likely to be diagnosed for TB during follow-up cares than those diagnosed before (AOR [95% CI]: 3.78 [1.69-8.43]). Nearly a third (28.7%) of all interviewed PLHIV self reported that they had been treated with IPT.

Conclusions

It can be concluded that ICF for TB and IPT among PLHIV in Addis Ababa need boosting. Hence, it is recommended to put into practice the national and global guidelines to improve ICF and IPT among PLHIV in the city.

【 授权许可】

   
2014 Denegetu and Dolamo; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150413023034453.pdf 198KB PDF download
【 参考文献 】
  • [1]The Global Fund to Fight AIDS, TB and Malaria (GFATM): Collaborative TB/HIV activities information Note. http://www.theglobalfund.org/documents/rounds/11/R11_TB/HIV_InfoNote_en/ webcite (accessed 21 October 2012)
  • [2]United Nations for AIDS Program (UNAIDS): Global Fund Information Note: TB/HIV Collaborative Activities. http://www.stoptb.org/assets/2012/02/21/global/ webcite TBHIVCollaborativeActivities (accessed 2 January 2013)
  • [3]World Health Organization (WHO): Global Tuberculosis Control 2011 Report. http://www.who.int/tb/2012/03/23/publications/global_report webcite (accessed 31 December 2012)
  • [4]World Health Organization (WHO): WHO policy on collaborative TB/HIV activities: Guidelines for national programmes and other stakeholders. http://whqlibdoc.who.int/publications/2012/9789241503006_eng.pdf webcite (accessed 14 April 2013)
  • [5]World Health Organization (WHO): WHO 3 I’s Meeting: Intensified Case Finding (ICF), Isoniazid Preventive Therapy (IPT) and TB Infection Control (IC) for people living with HIV: Report of a WHO Joint HIV and TB Department Meeting. http://www.who.int/hiv/pub/2012/10/23/meetingreports/WHO_3Is_meeting_report.pdf webcite (accessed 27 September 2012)
  • [6]World Health Organization (WHO): TB/HIV Monitoring and Advocacy Project Interview Tool. http://www.soros.org/sites/default/files/2011/10/10/ webcite interview-tool.pdf (accessed 9 June 2012)
  • [7]Federal Ministry of Health of Ethiopia (FMoH): Implementation Guideline for TB/HIV Collaborative Activities in Ethiopia. http://www.who.int/hiv/pub/guidelines/ethiopia.pdf webcite (accessed 29 December 2012)
  • [8]Getahun H, Gunneberg C, Granich R, Nunn P: HIV infection-associated tuberculosis: the epidemiology and the response. Clin Infect Dis 2010, 50(Suppl):3S201-3S207.
  • [9]Wesen A, Mitke G: Screening and case detection for tuberculosis among people living with HIV in Addis Ababa, Ethiopia. Ethiop Med J 2009, 47(2):109-115.
  • [10]Andrea AH, Wafaa ME: Integration of tuberculosis and HIV services in Sub-Saharan Africa: lessons learned. Clin Infect Dis 2010, 50(Suppl 3):S238-S244.
  • [11]Lawn SD, Motasim B, Wood R: Tuberculosis among HIV-infected patients receiving HAART: long term incidence and risk factors in a South African cohort. AIDS 2005, 19:2109-2116.
  • [12]Sonnenberg P, Glynn JR, Fielding K, Murray J, Godfrey-Faussett P, Shearer S: How soon after infection with HIV does the risk of tuberculosis start to increase? A retrospective cohort study in South African gold miners. J Infect Dis 2005, 191(2):150-158.
  • [13]Wessels J, Verkuijl S, Reed K, et al.: Integration of a TB screening tool into a comprehensive HIV adult clinical record in the Eastern Cape. South Africa: Fourth South African AIDS Conference, Durban; 2009. abstract 485. http://www.aidsmap.com/Integrated-screening-tool-improves-TB-screening-rate-in-HIV-patients-in-Eastern-Cape/page/1434145/ webcite] (accessed 20 December 2011
  • [14]Federal Democratic Republic of Ethiopia (FDRE): Report on progress towards implementation of the UN Declaration of Commitment on HIV/AIDS. http://data.unaids.org/pub/Report/2010/ethiopia_2010_country_progress_report_en.pdf webcite (accessed 17 February 2012)
  • [15]Chan CK, Alvarez BF, Wong KH, et al.: The epidemiology and clinical manifestations of human immunodeficiency virus-associated tuberculosis in Hong Kong. Hong Kong Med J 2010, 16(3):192-198.
  • [16]Memon AR, Memon MA, Altaf A, et al.: Frequency of dual tuberculosis/human immunodeficiency virus infection in patients presenting at tertiary care centres at Karachi. J Coll Physicians and Surgeons Pakistan 2007, 17(10):591-593.
  • [17]Gabunia P, Salakaia A, Kiria N, et al.: TB/HIV co infection in Georgia. Georgian Med News 2008, 165:7-10.
  • [18]Badri M, Wilson D, Wood R: Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study. Lancet 2002, 359:2059-2064.
  • [19]Lawn SD, Kranzer K, Wood R: Antiretroviral therapy for control of the HIV-associated tuberculosis epidemic in resource-limited settings. Clin Chest Med 2009, 30:685-699.
  • [20]Brodt HR, Kamps BS, Gute P, et al.: Changing incidence of AIDS-defining illnesses in the era of antiretroviral combination therapy. AIDS 1997, 11:1731-1738.
  • [21]Woldehanna S, Volmink J: Treatment of latent tuberculosis infection in HIV infected persons. Cochrane Database Syst Rev 2004, 1:CD000171.
  • [22]Grant AD, Charalambous S, Fielding KL, et al.: Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: a novel randomized incremental recruitment study. JAMA 2005, 293(22):2719-2725.
  • [23]Golub JE, Pronyk P, Mohapi L, et al.: Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa: a prospective cohort. AIDS 2009, 23(5):631-636.
  • [24]Haileyesus G, Reuben G, Delphine S, et al.: Implementation of Isoniazid preventive therapy for people living with HIV worldwide: barriers and solutions. AIDS 2010, 24(suppl 5):S57-S65.
  • [25]World Health Organization: Guidelines for intensified tuberculosis case-finding and Isoniazid preventive therapy for people living with HIV in resource- constrained settings. http://whqlibdoc.who.int/publications/2011/9789241500708_eng.pdf webcite (accessed 21 October 2013)
  • [26]Family Health International 360: Isoniazid Preventive Therapy for the Prevention of Tuberculosis in People Living with HIV/AIDS. http://www.fhi360.org/sites/default/files/webpages/IPT/index.html webcite (accessed 2 October 2013)
  文献评价指标  
  下载次数:6次 浏览次数:17次