Prevalence of chronic kidney disease in patients with type 2 diabetes in Spain: PERCEDIME2 study

BMC Nephrology

Gabriel Coll-de Tuero¹  Joan Barrot-De la Puente³  Xavier Mundet-Tuduri⁴  Javier Diez-Espino⁵  Josep Franch-Nadal²  Josep Garre-Olmo¹  Antonio Rodriguez-Poncelas¹ 

[1]Unitat de Recerca IAS, Salt, Spain

[2]Unitat de Recerca Jordi Gol, Barcelona, Spain

[3]EAP Salt, Girona, Spain

[4]EAP El Carmel, Barcelona, Spain

[5]EAP Tafalla, Navarra, Spain

关键词: Type 2 diabetes mellitus;    Albuminuria;    Renal impairment;    Chronic kidney disease;    Cross-sectional study;   

Others  :  1082992
DOI  :  10.1186/1471-2369-14-46

 received in 2012-09-14, accepted in 2013-02-12,  发布年份 2013

【 摘 要 】

Bakground

The objective of this study was to determinate the prevalence of chronic kidney disease (CKD) and the different stages of CKD in patients with type 2 diabetes mellitus (DM2) treated in primary care consults in Spain.

Methods

A national cross-sectional study was performed in primary care consults. The following data were collected: demographic and anthropometric information; list of present cardiovascular risk factors (CVRF); previous macrovascular and microvascular disease history; physical examination and analytical data from the previous 12 months, including the urine albumin-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) to evaluate renal function.

Results

With regard to the patients, 27.9% presented some degree of CKD as follows: 3.5% with stage 1; 6.4% with stage 2; 16.8% with stage 3 (11.6% with stage 3A and 5.2% with stage 3B); and 1.2% with stages 4 and 5. The prevalence of patients with UACR ≥ 30 mg/g was 15.4% (13% microalbuminuria and 2.4% macroalbuminuria). Renal impairment (RI) was found in 206 patients (18%) of whom 133 patients (64.6%) was stage 3A, 60 patients (29.1%) was stage 3B and 13 patients (6.3%) stages 4 and 5. Among patients with RI, 143 patients (69.4%) had normoalbuminuria.

The following variables were significantly associated with CKD: age; sex (women); systolic arterial blood pressure (SABP) ≥ 150 mmHg; and a previous history of cardiovascular disease.

Conclusions

The results showed that the prevalence for any type of CKD was 27.9%. A systematic determination of UACR and eGFR may contribute to an early diagnosis, thus allowing intervention during the initial stages of the disease when treatment is more efficient.

【 授权许可】

   
2013 Rodriguez-Poncelas et al; licensee BioMed Central Ltd.

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