Incidence, histopathologic analysis and distribution of tumours of the hand

BMC Musculoskeletal Disorders

Florian Barvencik²  Michael Amling²  Jozef Zustin¹  Matthias Krause²  Felix Hövelborn²  Pia Pogoda²  Maciej JK Simon² 

[1] Institute of Pathology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany;Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany

关键词: Radiography;    Incidence;    Histopathology;    Tumours;    Hand;   

Others  :  1125639
DOI  :  10.1186/1471-2474-15-182

 received in 2013-09-04, accepted in 2014-05-23,  发布年份 2014

【 摘 要 】

Background

The aim of this large collective and meticulous study of primary bone tumours and tumourous lesions of the hand was to enhance the knowledge about findings of traumatological radiographs and improve differential diagnosis.

Methods

This retrospective study reviewed data collected from 1976 until 2006 in our Bone Tumour Registry. The following data was documented: age, sex, radiological investigations, tumour location, histopathological features including type and dignity of the tumour, and diagnosis.

Results

The retrospective analysis yielded 631 patients with a mean age of 35.9 ± 19.2 years. The majority of primary hand tumours were found in the phalanges (69.7%) followed by 24.7% in metacarpals and 5.6% in the carpals. Only 10.6% of all cases were malignant. The major lesion type was cartilage derived at 69.1%, followed by bone cysts 11.3% and osteogenic tumours 8.7%. The dominant tissue type found in phalanges and metacarpals was of cartilage origin. Osteogenic tumours were predominant in carpal bones. Enchondroma was the most commonly detected tumour in the hand (47.1%).

Conclusions

All primary skeletal tumours can be found in the hand and are most often of cartilage origin followed by bone cysts and osteogenic tumours. This study furthermore raises awareness about uncommon or rare tumours and helps clinicians to establish proper differential diagnosis, as the majority of detected tumours of the hand are asymptomatic and accidental findings on radiographs.

【 授权许可】

   
2014 Simon et al.; licensee BioMed Central Ltd.

【 图 表 】

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