In-vitro assessment of coronary artery stents in 256-multislice computed tomography angiography

BMC Research Notes

Henning Steen³  Hugo A Katus³  Hans-Ulrich Kauczor¹  Waldemar Hosch¹  Grigorios Korosoglou³  Dirk Müller²  Florian André³ 

[1] Department of Diagnostic and Interventional Radiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany;Philips GmbH Healthcare Division, Luebeckertordamm 5, Hamburg 20099, Germany;Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, Heidelberg 69120, Germany

关键词: Technology assessment;    Heart;    In-stent restenosis;    Coronary artery stents;    CT angiography;   

Others  :  1134842
DOI  :  10.1186/1756-0500-7-38

 received in 2013-08-01, accepted in 2013-12-30,  发布年份 2014

【 摘 要 】

Background

The important detection of in-stent restenosis in cardiovascular computed tomography (CT) is still challenging. The first study assessing the in-vitro stent lumen visualization of the state of the art 256-multislice CT (256-MSCT), which was performed by our research group, yielded promising results. As the applied technical approach is not suitable for daily routine, we assessed the capability of the 256-MSCT and its different reconstruction kernels for the coronary stent lumen visualization employing a clinically applicable technique in a phantom study.

Results

The XCD kernel showed significantly lower artificial lumen narrowing (ALN) values (overall ALN < 40%) than the other reconstruction kernels (CC, CD, XCB) irrespective of the stent caliber. The ALN of coronary stents with a diameter >3 mm was significantly lower than of stents with a smaller caliber. The ALN difference between stents with a diameter of 3 mm and smaller ones was not statistically significant. Yet, the lumen visualization of the smaller stents was impaired by a halo effect. The XCD kernel showed more constant attenuation values throughout the different stent diameters than the other reconstruction kernels.

Conclusions

The 256-MSCT provides a good lumen visualization of coronary stents with a diameter >3 mm. The assessment of stents with a diameter of 3 mm seems feasible but has to be validated in further studies. The clinical evaluation of smaller stents cannot be recommended so far. The XCD kernel showed the best lumen visualization and should therefore be applied in addition to the standard cardiac reconstruction kernels when assessing coronary artery stents using 256-MSCT.

【 授权许可】

   
2014 André et al.; licensee BioMed Central Ltd.

【 图 表 】

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