Community-acquired diarrhea among children and adults in urban settings in Senegal: clinical, epidemiological and microbiological aspects

BMC Infectious Diseases

Amy Gassama-Sow¹  Mbacké Sembene¹  Lassina Gadi Timbiné²  Mamadou Elimane Faye²  Emmanuelle Espié³  Bissoume Sambe-Ba² 

[1] University Cheikh Anta Diop, Dakar, Senegal;Experimental Bacteriology Unit, Pasteur Institute of Dakar, 36 avenue Pasteur, BP 220 Dakar, Senegal;Epidemiology Unit, Pasteur Institute of Dakar, Dakar, Senegal

关键词: sub-Saharan Africa;    Adults;    Children;    Parasite;    Virus;    Bacteria;    Diarrhea;   

Others  :  1145317
DOI  :  10.1186/1471-2334-13-580

 received in 2013-04-29, accepted in 2013-12-02,  发布年份 2013

【 摘 要 】

Background

Only limited data are available relating to the etiology of diarrhea in children and adults in Senegal. The aim of this prospective study was to describe the epidemiology and etiology of community-acquired diarrheal infections in children and adults living in urban settings.

Methods

A prospective study was carried out from March 2009 to December 2010, in the urban region of Dakar, Senegal. Patients with acute diarrhea were enrolled, interviewed to collect their clinical history, and their stools were tested for bacteria, virus and parasites.

Results

A total of 223 patients (including 112 children younger than five years old) with diarrhea were included. At least one enteropathogen was detected in 81% (180/223) of the patients: 29% (64/223) had bacterial infections (mainly diarrheagenic E. coli and Shigella spp), 21% (39/185) viral infections (mainly rotavirus) and 14% (31/223) parasitic infections. Co-infection was identified in 17.8% (32/180) of the patients. Viral infection was significantly more frequent in children under five years old during the dry season. Bacteria and parasites were equally frequent in all age groups. There was a seasonal variation of bacterial infections during the study period, with a higher proportion of infections being bacterial, and due to Salmonella spp. in particular, during the rainy season.

Conclusion

Our study suggests that in urban settings in Senegal, rotavirus is the principal cause of pediatric diarrhea during the dry season and that the proportion of bacterial infections seems to be higher during the rainy season. Further work is needed to document the burden of diarrheal diseases in sub-Saharan urban communities and to identify risk factors, including those linked to the rapid and unplanned urbanization in Africa.

【 授权许可】

   
2013 Sambe-Ba et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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