Long-standing insulinoma: two case reports and review of the literature

BMC Research Notes

Khalid Sair²  Mohammed Elfahssi²  Mohamed Oukabli³  Yassir Sbitti¹  Mohamed Bouzroud²  El Mehdi Aboulfeth²  Mohamed Essarghini²  Mohamed said Belhamidi²  Moulay Brahim Ratbi²  Abdelmounaim Ait Ali²  Mohamed Tarchouli² 

[1] Department of Oncology, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco;Department of Digestive Surgery, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco;Department of Pathology, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat, Morocco

关键词: Surgery;    Management;    Diagnosis;    Pancreas;    Insulinoma;   

Others  :  1230147
DOI  :  10.1186/s13104-015-1424-1

 received in 2015-04-03, accepted in 2015-09-07,  发布年份 2015

【 摘 要 】

Background

Insulinomas are rare pancreatic endocrine tumors. Most are benign and solitary. However, the nonspecific symptoms and small size of these tumors led to difficulties of diagnosis and localization.

Case presentation

We present two Arab patients with pancreatic long-standing insulinoma. Both patients presented episodic hypoglycemic symptoms respectively during 10 and 2 years. Biochemical and morphological workup detected localized pancreatic insulinoma. Open procedure surgery was done for the two patients and insulinomas were successfully removed by enucleation.

Conclusion

Insulinoma remains a diagnostic challenge to practitioners. Diagnosis of suspected cases is easily confirmed by standard endocrine tests, especially the supervised fasting test. Accurate preoperative localization is essential for more effective and safest surgery.

【 授权许可】

   
2015 Tarchouli et al.

【 图 表 】

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