Unexpected outcome after sclerotherapy of simple renal cyst

BMC Nephrology

Chikara Ohyama²  Takuya Koie²  Hisao Saitoh¹  Atsushi Sasaki¹  Noriko Tokui¹  Atsushi Imai¹  Yasuhiro Hashimoto² 

[1]Oyokyo Kidney Research Institute Hirosaki Hospital, 90 Yamazaki Kozawa, Hirosaki, Aomori 036-8243, Japan

[2]Department of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki, Aomori 036-8562, Japan

关键词: Malignant transformation;    Sclerotherapy;    Simple renal cyst;    Papillary renal cell carcinoma;   

Others  :  1083150
DOI  :  10.1186/1471-2369-13-63

 received in 2012-01-17, accepted in 2012-07-24,  发布年份 2012

【 摘 要 】

Background

Simple renal cysts usually have benign clinical features. We report a rare case of papillary renal cell carcinoma (RCC) associated with a large recurrent simple cyst following sclerotherapy.

Case Presentation

A 47-year-old Japanese woman received minocycline sclerotherapy for a large (9 cm in diameter) simple left renal cyst in May 2005. The cyst regrew, and second-line sclerotherapy with ethanol was performed in November 2005. Three years later, she developed papillary RCC on the wall of the recurrent renal cyst. Radical nephrectomy was performed, but the patient died of metastatic disease 15 months after surgery.

Conclusion

Malignant transformation from recurrent simple renal cyst to RCC may occur in the years following sclerotherapy, underscoring the need for long-term follow-up.

【 授权许可】

   
2012 Hashimoto et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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