Unexpected outcome after sclerotherapy of simple renal cyst

BMC Nephrology

Case Report

Chikara Ohyama¹  Takuya Koie¹  Atsushi Sasaki²  Atsushi Imai²  Noriko Tokui²  Hisao Saitoh²  Yasuhiro Hashimoto³ 

[1]Department of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, 036-8562, Hirosaki, Aomori, Japan

[2]Oyokyo Kidney Research Institute Hirosaki Hospital, 90 Yamazaki Kozawa, 036-8243, Hirosaki, Aomori, Japan

[3]Oyokyo Kidney Research Institute Hirosaki Hospital, 90 Yamazaki Kozawa, 036-8243, Hirosaki, Aomori, Japan

[4]Department of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, 036-8562, Hirosaki, Aomori, Japan

关键词: Papillary renal cell carcinoma;    Simple renal cyst;    Sclerotherapy;    Malignant transformation;   

DOI  :  10.1186/1471-2369-13-63

 received in 2012-01-17, accepted in 2012-07-24,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundSimple renal cysts usually have benign clinical features. We report a rare case of papillary renal cell carcinoma (RCC) associated with a large recurrent simple cyst following sclerotherapy.Case PresentationA 47-year-old Japanese woman received minocycline sclerotherapy for a large (9 cm in diameter) simple left renal cyst in May 2005. The cyst regrew, and second-line sclerotherapy with ethanol was performed in November 2005. Three years later, she developed papillary RCC on the wall of the recurrent renal cyst. Radical nephrectomy was performed, but the patient died of metastatic disease 15 months after surgery.ConclusionMalignant transformation from recurrent simple renal cyst to RCC may occur in the years following sclerotherapy, underscoring the need for long-term follow-up.

【 授权许可】

CC BY   
© Hashimoto et al.; licensee BioMed Central Ltd. 2012