Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing

BMC Genomics

Hyung Wook Kwon⁷  Gyoungju Nah⁵  Owain R Edwards⁴  Tae-Jin Yang⁵  Ik-Young Choi¹  Yoonseong Park²  Myeong-Lyeol Lee⁶  Yong-Soo Choi⁶  Yeisoo Yu³  Jongsung Lim¹  Jeongsoo Lee¹  Murukarthick Jayakodi⁵  Beom-Soon Choi¹  Je Won Jung⁷  Doori Park⁷ 

[1] National Instrumentation Center for Environmental Management, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-742, Republic of Korea;Department of Entomology, Kansas State University, Manhattan, Kansas, USA;Arizona Genomics Institute, University of Arizona, Tucson, Arizona 85721, USA;CSIRO Ecosystem Sciences, Centre for Environment and Life Sciences, Underwood Avenue, Floreat, WA 6014, Australia;Department of Plant Science, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea;National Institute of Agricultural Biotechnology, Rural development Administration, Suwon 441-707, Republic of Korea;Biomodulation Major, Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea

关键词: Honey bee immunity;    Chemosensory receptors;    Social insect;    Genome;    Asian honey bee;    Apis cerana;   

Others  :  1121412
DOI  :  10.1186/1471-2164-16-1

 received in 2014-08-01, accepted in 2014-12-02,  发布年份 2015

【 摘 要 】

Background

The honey bee is an important model system for increasing understanding of molecular and neural mechanisms underlying social behaviors relevant to the agricultural industry and basic science. The western honey bee, Apis mellifera, has served as a model species, and its genome sequence has been published. In contrast, the genome of the Asian honey bee, Apis cerana, has not yet been sequenced. A. cerana has been raised in Asian countries for thousands of years and has brought considerable economic benefits to the apicultural industry. A cerana has divergent biological traits compared to A. mellifera and it has played a key role in maintaining biodiversity in eastern and southern Asia. Here we report the first whole genome sequence of A. cerana.

Results

Using de novo assembly methods, we produced a 238 Mbp draft of the A. cerana genome and generated 10,651 genes. A.cerana-specific genes were analyzed to better understand the novel characteristics of this honey bee species. Seventy-two percent of the A. cerana-specific genes had more than one GO term, and 1,696 enzymes were categorized into 125 pathways. Genes involved in chemoreception and immunity were carefully identified and compared to those from other sequenced insect models. These included 10 gustatory receptors, 119 odorant receptors, 10 ionotropic receptors, and 160 immune-related genes.

Conclusions

This first report of the whole genome sequence of A. cerana provides resources for comparative sociogenomics, especially in the field of social insect communication. These important tools will contribute to a better understanding of the complex behaviors and natural biology of the Asian honey bee and to anticipate its future evolutionary trajectory.

【 授权许可】

   
2015 Park et al.; licensee BioMed Central.

【 图 表 】

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