Enzyme promiscuity: using the dark side of enzyme specificity in white biotechnology

Sustainable Chemical Processes

Benu Arora²  Joyeeta Mukherjee²  Munishwar Nath Gupta¹ 

[1] Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India

[2] Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi 110016, India

关键词: Green chemistry;    Enantioselectivity;    Enzymes in organic synthesis;    Catalytic promiscuity;    Enzyme specificity;   

Others  :  1216787
DOI  :  10.1186/s40508-014-0025-y

 received in 2014-08-27, accepted in 2014-12-10,  发布年份 2014

【 摘 要 】

Enzyme promiscuity can be classified into substrate promiscuity, condition promiscuity and catalytic promiscuity. Enzyme promiscuity results in far larger ranges of organic compounds which can be obtained by biocatalysis. While early examples mostly involved use of lipases, more recent literature shows that catalytic promiscuity occurs more widely and many other classes of enzymes can be used to obtain diverse kinds of molecules. This is of immense relevance in the context of white biotechnology as enzyme catalysed reactions use greener conditions.

【 授权许可】

   
2014 Arora et al.; licensee Springer.

【 图 表 】

Figure 1.

Figure 2.

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