Assessment of postoperative pain after unilateral mastectomy using two different surgical techniques in dogs

Acta Veterinaria Scandinavica

Bruno W Minto¹  Lisiane C Rodrigues¹  Paulo VM Steagall¹  Eduardo R Monteiro¹  Claudia VS Brandão¹ 

[1] Department of Veterinary Clinics and Surgery, School of Veterinary Medicine and Animal Science, Sao Paulo State University, UNESP, Via de Acesso Prof. Paulo Roberto Castellane s/n, Jaboticabal, SP, Brazil

关键词: Surgery;    Analgesia;    Mastectomy;    Cancer;    Dog;   

Others  :  789275
DOI  :  10.1186/1751-0147-55-60

 received in 2013-01-24, accepted in 2013-08-18,  发布年份 2013

【 摘 要 】

Background

There are few studies reporting pain and postoperative analgesia associated with mastectomy in dogs. The aim of this study was to evaluate postoperative pain after unilateral mastectomy using two different surgical techniques in the dog.

Findings

Twenty female dogs were assigned (n=10/group) to undergo unilateral mastectomy using either the combination of sharp and blunt dissection (SBD) or the modified SBD (mSBD) technique, in which the mammary chain is separated from the abdominal wall entirely by blunt (hand and finger) dissection except for a small area cranial to the first gland, in a prospective, randomized, clinical trial. All dogs were premedicated with intramuscular acepromazine (0.05 mg/kg) and morphine (0.3 mg/kg). Anesthesia was induced with intravenous ketamine (5 mg/kg) and diazepam (0.25 mg/kg), and maintained with isoflurane. Subcutaneous meloxicam (0.2 mg/kg) was administered before surgery. Postoperative pain was evaluated according to the University of Melbourne pain scale (UMPS) by an observer who was blinded to the surgical technique.. Rescue analgesia was provided by the administration of intramuscular morphine (0.5 mg/kg) if pain scores were >14 according to the UMPS. Data were analyzed using t-tests and ANOVA (P>0.05). There were no significant differences between the groups for age, weight, extubation time, and duration of surgery and anesthesia (P>0.05). There were no significant differences for postoperative pain scores between groups. Rescue analgesia was required in one dog in each group.

Conclusions

The two surgical techniques produced similar surgical times, incidence of perioperative complications and postoperative pain. Multimodal analgesia is recommended for treatment of postoperative pain in dogs undergoing unilateral mastectomy.

【 授权许可】

   
2013 Minto et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Lana SE, Rutterman GR: Tumors of the Mammary Gland. In Small Animal Clinical Oncology. 4th edition. Edited by Withrow SJ, MacEven EG. St. Louis: W.B. Saunders; 2007:619-636.
• [2]Sleeckx N, de Rooster H, Veldhuis Kroeze E, Van Ginneken C, Van Brantegem L: Canine mammary tumours, an overview. Reprod Domest Anim 2011, 46:1112-1131.
• [3]Stratmann N, Failing K, Ritchter A, Wehrend A: Mammary tumor recurrence in bitches after regional mastectomy. Vet Surg 2008, 37:82-86.
• [4]Steagall PVM, Teixeira Neto FJ, Minto BW, Campagnol DC, Correa MA: Evaluation of the isoflurane-sparing effects of lidocaine and fentanyl during surgery in dogs. J Am Vet Med Assoc 2006, 229:522-527.
• [5]Sarrau S, Jourdan J, Dupuis-Soyris F, Verwaverde P: Effects of postoperative ketamine infusion on pain control and feeding behaviour in bitches undergoing mastectomy. J Small Anim Pract 2007, 48:670-676.
• [6]Nakagawa K, Miyagawa Y, Takemura N, Hirose H: Influence of preemptive analgesia with meloxicam before resection of the unilateral mammary gland on postoperative cardiovascular parameters in dogs. J Vet Med Sci 2007, 69:939-944.
• [7]Gakiya HH, Silva DA, Gomes J, Stevanin H, Cassu RN: Electroacupunture versus morphine for the postoperative control pain in dogs. Acta Cir Bras 2011, 26:346-351.
• [8]Harvey HJ: Mammary glands. In Current Techniques in Small Animal Surgery. 4th edition. Edited by Bojrab MJ. Philadelphia: Lea and Febiger; 1998:579-584.
• [9]Firth AM, Haldane SL: Development of a scale to evaluate postoperative pain in dogs. J Am Vet Med Assoc 1999, 214:651-659.