The characteristics of bacterial nanocellulose gel releasing silk sericin for facial treatment

BMC Biotechnology

Pornanong Aramwit¹  Nipaporn Bang¹ 

[1] Bioactive Resources for Innovative Clinical Applications Research Unit and Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, PhayaThai Road, Phatumwan 10330, Bangkok, Thailand

关键词: Facial mask;    Silk sericin;    Coconut water;    Gluconacetobacter xylinus;    Bacterial nanocellulose;   

Others  :  1084329
DOI  :  10.1186/s12896-014-0104-x

 received in 2014-05-14, accepted in 2014-11-27,  发布年份 2014

【 摘 要 】

Background

Recently, naturally derived facial masks with beneficial biological properties have received increasing interest. In this study, silk sericin-releasing bacterial nanocellulose gel was developed to be applied as a bioactive mask for facial treatment.

Results

The silk sericin-releasing bacterial nanocellulose gel produced at a pH of 4.5 had an ultrafine and extremely pure fiber network structure. The mechanical properties and moisture absorption ability of the gel were improved, compared to those of the commercially available paper mask. Silk sericin could be control-released from the gel. A peel test with porcine skin showed that the gel was less adhesive than the commercially available paper mask, which would be removed from the face more easily without pain. The in vitro cytotoxicity test showed that the gel was not toxic to L929 mouse fibroblast and HaCaT human keratinocyte cells. Furthermore, when implanted subcutaneously and evaluated according to ISO10993-6 standard, the gel was not irritant to tissue.

Conclusion

The silk sericin-releasing bacterial nanocellulose gel had appropriate physical and biological properties and safety for the facial treatment application.

【 授权许可】

   
2014 Aramwit and Bang; licensee BioMed Central Ltd.

【 图 表 】

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