BioMedical Engineering OnLine | |
Design and testing of an MRI-compatible cycle ergometer for non-invasive cardiac assessments during exercise | |
Silmara Gusso1  Carlo Salvador3  Paul Hofman5  Wayne Cutfield1  James C Baldi2  Andrew Taberner4  Poul Nielsen4  | |
[1] Liggins Institute, University of Auckland, Auckland, New Zealand | |
[2] Department of Medicine, University of Otago, Otago, New Zealand | |
[3] Department of Engineering Science, University of Auckland, Auckland, New Zealand | |
[4] Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand | |
[5] Liggins Institute, University of Auckland, 2-6 Park Ave, Grafton, Auckland, New Zealand | |
关键词: Magnetic resonance imaging; Left ventricular function; Cycle ergometer; | |
Others : 798115 DOI : 10.1186/1475-925X-11-13 |
|
received in 2011-09-06, accepted in 2012-03-18, 发布年份 2012 | |
【 摘 要 】
Background
Magnetic resonance imaging (MRI) is an important tool for cardiac research, and it is frequently used for resting cardiac assessments. However, research into non-pharmacological stress cardiac evaluation is limited.
Methods
We aimed to design a portable and relatively inexpensive MRI cycle ergometer capable of continuously measuring pedalling workload while patients exercise to maintain target heart rates.
Results
We constructed and tested an MRI-compatible cycle ergometer for a 1.5 T MRI scanner. Resting and sub-maximal exercise images (at 110 beats per minute) were successfully obtained in 8 healthy adults.
Conclusions
The MRI-compatible cycle ergometer constructed by our research group enabled cardiac assessments at fixed heart rates, while continuously recording power output by directly measuring pedal force and crank rotation.
【 授权许可】
2012 Gusso et al; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20140706101538423.pdf | 1343KB | download | |
Figure 6. | 57KB | Image | download |
Figure 5. | 60KB | Image | download |
Figure 4. | 46KB | Image | download |
Figure 3. | 45KB | Image | download |
Figure 2. | 57KB | Image | download |
Figure 1. | 58KB | Image | download |
【 图 表 】
Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Figure 6.
【 参考文献 】
- [1]Bottini PB, Carr AA, Prisant LM, Flickinger FW, Allison JD, Gottdiener JS: Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient. Am J Hypertens 1995, 8:221-228.
- [2]Missouris CG, Forbat SM, Singer DR, Markandu ND, Underwood R, MacGregor GA: Echocardiography overestimates left ventricular mass: a comparative study with magnetic resonance imaging in patients with hypertension. J Hypertens 1996, 14:1005-1010.
- [3]Sandstede J, Lipke C, Beer M, Hofmann S, Pabst T, Kenn W, Neubauer S, Hahn D: Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging. Eur Radiol 2000, 10:438-442.
- [4]Jochims M, Bruder O, Jensen C, Sabin G: High-dose dobutamine stress cardiac MR imaging for detection of myocardial ischemia. Magnetom 2007, 2:42-49.
- [5]Cheng CP, Schwandt DF, Topp EL, Anderson JH, Herfkens RJ, Taylor CA: Dynamic exercise imaging with an MR-compatible stationary cycle within the general electric open magnet. Magn Reson Med 2003, 49:581-585.
- [6]Pedersen EM, Kozerke S, Ringgaard S, Scheidegger MB, Boesiger P: Quantitative abdominal aortic flow measurements at controlled levels of ergometer exercise. Magn Reson Imaging 1999, 17:489-494.
- [7]Roest AA, Kunz P, Lamb HJ, Helbing WA, van der Wall EE, de Roos A: Biventricular response to supine physical exercise in young adults assessed with ultrafast magnetic resonance imaging. Am J Cardiol 2001, 87:601-605.
- [8]Roest AA, Lamb HJ, van der Wall EE, Vliegen HW, van den Aardweg JG, Kunz P, de Roos A, Helbing WA: Cardiovascular response to physical exercise in adult patients after atrial correction for transposition of the great arteries assessed with magnetic resonance imaging. Heart 2004, 90:678-684.
- [9]Taylor CA, Cheng CP, Espinosa LA, Tang BT, Parker D, Herfkens RJ: In vivo quantification of blood flow and wall shear stress in the human abdominal aorta during lower limb exercise. Ann Biomed Eng 2002, 30:402-408.
- [10]Laperriere AR, VanDercar DH, Shyu LY, Ward MF, McCabe PM, Perry AC, Mosher PE, Schneiderman N: Microcomputer servo-controlled bicycle ergometer system for psychophysiological research. Psychophysiology 1989, 26:201-207.
- [11]Raymer GH, Allman BL, Rice CL, Marsh GD, Thompson RT: Characteristics of a MR-compatible ankle exercise ergometer for a 3.0 T head-only MR scanner. Med Eng Phys 2006, 28:489-494.
- [12]Quistorff B, Nielsen S, Thomsen C, Jensen KE, Henriksen O: A simple calf muscle ergometer for use in a standard whole-body MR scanner. Magn Reson Med 1990, 13:444-449.
- [13]Jeneson JA, Schmitz JP, Hilbers PA, Nicolay K: An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing. Magn Reson Med 2010, 63:257-261.
- [14]Holverda S, Gan CT, Marcus JT, Postmus PE, Boonstra A, Vonk-Noordegraaf A: Impaired stroke volume response to exercise in pulmonary arterial hypertension. J Am Coll Cardiol 2006, 47:1732-1733.
- [15]Dash R, Torffvit O: How to predict nephropathy in type 1 diabetic patients. Scand J Urol Nephrol 2003, 37:437-442.
- [16]Nelson RR, Gobel FL, Jorgensen CR, Wang K, Wang Y, Taylor HL: Hemodynamic predictors of myocardial oxygen consumption during static and dynamic exercise. Circulation 1974, 50:1179-1189.
- [17]Baldi JC, McFarlane K, Oxenham HC, Whalley GA, Walsh HJ, Doughty RN: Left ventricular diastolic filling and systolic function of young and older trained and untrained men. J Appl Physiol 2003, 95:2570-2575.
- [18]Chung CS, Karamanoglu M, Kovacs SJ: Duration of diastole and its phases as a function of heart rate during supine bicycle exercise. Am J Physiol Heart Circ Physiol 2004, 287:H2003-H2008.
- [19]Rowell LB: Human Circulation Regulation During Physical Stress. New York: Oxford University Press; 1986.
- [20]Gledhill N, Cox D, Jamnik R: Endurance athletes' stroke volume does not plateau: major advantage is diastolic function. Med Sci Sports Exerc 1994, 26:1116-1121.
- [21]Gonzalez-Alonso J, Mora-Rodriguez R, Coyle EF: Stroke volume during exercise: interaction of environment and hydration. Am J Physiol Heart Circ Physiol 2000, 278:H321-H330.
- [22]Zhou B, Conlee RK, Jensen R, Fellingham GW, George JD, Fisher AG: Stroke volume does not plateau during graded exercise in elite male distance runners. Med Sci Sports Exerc 2001, 33:1849-1854.
- [23]Schairer JR, Stein PD, Keteyian S, Fedel F, Ehrman J, Alam M, Henry JW, Shaw T: Left ventricular response to submaximal exercise in endurance-trained athletes and sedentary adults. Am J Cardiol 1992, 70:930-933.