The effects of excess calcium on the handling and mechanical properties of hydrothermal derived calcium phosphate bone cement

International Conference on Advances in Manufacturing and Materials Engineering 2017

机械制造;材料科学

Razali, N.N.^1 ; Sukardi, M.A.^1 ; Sopyan, I.^1 ; Mel, M.^2 ; Salleh, H.M.^2 ; Rahman, M.M.^3

Department of Manufacturing and Materials Engineering, Faculty of Engineering, International Islamic University Malaysia, Kuala Lumpur

50728, Malaysia^1

Department of Biotechnology Engineering, Faculty of Engineering, International Islamic University Malaysia, Kuala Lumpur

50728, Malaysia^2

Department of Mechanical Engineering, Faculty of Engineering, Universiti Tenaga Nasional, Kajang, Selangor

43000, Malaysia^3

关键词: Ammonium dihydrogen phosphate;    Calcium phosphate bone cement;    Calcium phosphate cement;    Distilled water;    Hydrothermal methods;    Hydroxyapatite powder;    Morphological properties;    Synthesized powder;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/290/1/012053/pdf
DOI  :  10.1088/1757-899X/290/1/012053

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

The objective of this study is to determine the effects of excess calcium on the handling and mechanical properties of hydrothermal derived calcium phosphate cement (CPC) for bone filling applications. Hydroxyapatite powder was synthesized via hydrothermal method using calcium oxide, CaO and ammonium dihydrogen phosphate, NH4H2PO4as the calcium and phosphorus precursors respectively. The effects of calcium excess were evaluated by varying the CaO content at 0, 5 and 15 mole %. The precursors were then refluxed in distilled water at 90-100°C and dried overnight until the calcium phosphate powder was formed. CPC was then produced by mixing the synthesized powder with distilled water at the powder-to-liquid (P/L) ratio of 1.5. The result from the morphological properties of CPC shows the increase in agglomeration and particles size with 5 mole % of calcium excess but decreased with 15 mole % of calcium excess in CPC. This result was in agreement with the compressive strength result where the CPC increased its strength with 5 mole % of calcium excess but reduced with 15 mole % of calcium excess. The excess in calcium precursor also significantly improved the setting time but reduced the injectability of CPC.