Preparation of glucose sensors using gold nanoparticles modified diamond electrode

International Symposium on Current Progress in Functional Materials

Fachrurrazie^1 ; Ivandini, T.A.^1 ; Wibowo, W.^1

Department of Chemistry, Faculty of Mathematics, Natural Sciences Universitas Indonesia, Kampus UI Depok, Depok

16424, Indonesia^1

关键词: Boron doped diamond;    Boron-doped diamond electrodes;    Concentration ranges;    Cyclic voltammograms;    Diamond electrode;    Electrode surfaces;    Glucose oxidases (GOx);    Phosphate buffer solutions;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/188/1/012046/pdf
DOI  :  10.1088/1757-899X/188/1/012046

来源: IOP

【 摘 要 】

A glucose sensor was successfully developed by immobilizing glucose oxidase (GOx) at boron-doped diamond (BDD) electrodes. Prior to GOx immobilization, the BDD was modified with gold nanoparticles (AuNPs). To immobilize AuNPs, the gold surface was modified to nitrogen termination. The characterization of the electrode surface was performed using an X-ray photoelectron spectroscopy and a scanning electron microscope, while the electrochemical properties of the enzyme electrode were characterized using cyclic voltammetry. Cyclic voltammograms of the prepared electrode for D-glucose in phosphate buffer solution pH 7 showed a new reduction peak at +0.16 V. The currents of the peak were linear in the concentration range of 0.1 M to 0.9 M, indicated that the GOx-AuNP-BDD can be applied for electrochemical glucose detection.