Ferrum nano particles and multiwall carbon nano tubes based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids

1st International Conference on New Material and Chemical Industry

材料科学;化学工业

Sun, L.^1 ; Wang, J.^1 ; Wang, Y.T.^1 ; Yu, L.^1 ; Peng, H.^1 ; Zhu, J.Z.^1

School of Chemistry and Chemical Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai

200062, China^1

关键词: Amperometric electrodes;    Concentration ranges;    Fe nanoparticles;    Flow-injection analysis;    Guinea pigs;    Linear response;    Micro-dialysis;    Separation column;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/167/1/012025/pdf
DOI  :  10.1088/1757-899X/167/1/012025

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. Combined with Flow Injection Analysis (FIA) and chromatography separation column, the electrode exhibits linear response in the concentration range of 0.1 -12 μM and the sensitivity of 30.0 nA μM-1for most of amino acids. The determination of 17 amino acids in the hypothalamus microdialysis fluids of Guinea pigs, illustrates that the electrode is a powerful tool to investigate physiology and pathology mechanisms.