Characterization of cell cultures in contact with different orthopedic implants biomaterials

7th International Conference on Advanced Concepts in Mechanical Engineering

Ouenzerfi, G.^1,3 ; Hannoun, A.^1 ; Hassler, M.^3 ; Brizuela, L.^2 ; Youjil, S.^2 ; Bougault, C.^2 ; Trunfio-Sfarghiu, A.-M.^1

Contact and Structure Mechanics Laboratory, INSA of Lyon, France^1

Institut de Chimie et de Biochimie Moléculaires et Supramoléculaires (ICBMS), ODMB Laboratory, France^2

Wright Medical, France^3

关键词: Biological characterization;    Cellular levels;    Joint implants;    Living tissues;    Mechanical characterizations;    Mechanical constraints;    Orthopedic implant;    Pyrolytic carbon;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/147/1/012015/pdf
DOI  :  10.1088/1757-899X/147/1/012015

来源: IOP

【 摘 要 】

The aim of this study is to identify the role of biological and mechanical constraints (at the cellular level) surrounding living tissues (cartilage and bone) in the presence of different joint implant biomaterials. In this fact, cells cultures in the presence of different types of biomaterials (pyrolytic carbon, cobalt-Chromium, titanium) has been performed. These cell cultures were subjected to biological characterization tests and mechanical characterization. The obtained results correlate with the in vivo observations (a promotion of the creation of a neocartilagical tissue in contact with the Pyrolytic Carbon implants).