Integrative Modeling of Electrical Properties of Pacemaker Cardiac Cells

4th International Conference on Modern Technologies for Non-Destructive Testing

材料科学;物理学

Grigoriev, M.^1 ; Babich, L.^1

National Research Tomsk Polytechnic University, Tomsk, Russia^1

关键词: Cardiac cell;    Electrical potential;    Integrative modeling;    Intercellular spaces;    Molar concentration;    Transmembrane currents;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/132/1/012007/pdf
DOI  :  10.1088/1757-899X/132/1/012007

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

This work represents modeling of electrical properties of pacemaker (sinus) cardiac cells. Special attention is paid to electrical potential arising from transmembrane current of Na+, K+and Ca2+ions. This potential is calculated using the NaCaX model. In this respect, molar concentration of ions in the intercellular space which is calculated on the basis of the GENTEX model is essential. Combined use of two different models allows referring this approach to integrative modeling.