Metal nanoparticles in DBS card materials modification

3rd International Youth Conference on Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology

物理学;医药卫生;生态环境科学

Metelkin, A.^1 ; Frolov, G.^1 ; Kuznetsov, D.^1 ; Kolesnikov, E.^1 ; Chuprunov, K.^1 ; Kondakov, S.^1,2 ; Osipov, A.^1,2 ; Samsonova, J.^1,2

National Research Technological University MISIS, 2, Leninsky Ave., Moscow

119049, Russia^1

M.V. Lomonosov Moscow State University, Department of Chemistry, 1-3 Lenin Hills, Moscow

119991, Russia^2

关键词: Anti-bacterial activity;    Antibacterial effects;    Antibacterial properties;    Dried blood spot (DBS);    Low temperature plasmas;    Materials modification;    Nanoparticle coatings;    Nanostructured coatings;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/98/1/012020/pdf
DOI  :  10.1088/1757-899X/98/1/012020

来源: IOP

【 摘 要 】

In the recent years the method of collecting and storing Dried Blood Spots (DBS) on special cellulose membrane (paper) has gained wide popularity. But possible damage of biosamples caused by microorganisms in case of their incomplete drying is a disadvantage of the method. It can be overcome by treating sample-collection membranes with colloidal solutions of metal nanoparticles, having antibacterial effect. The team studied antibacterial properties of nonwoven material samples with various coatings (alcohol sols of copper, aluminium, iron, titanium, silver and vanadium nanoparticles). Colloidal solutions of nanoparticles were obtained by means of electroerosion method with further low-temperature plasma condensation. Antibacterial activity of fiberglass and cellulose membrane samples with nanoparticle coatings was studied using B. cereus and plaque bacteria cultures. It was revealed that nanostructured coatings can suppress bacterial activity; in addition they can diffuse from the membrane surface into medium which leads to widening the areas of inhibiting testing cultures' growth. Thus, membrane materials treatment with alcohol-sols of metal nanoparticles can be seen as promising for conferring antibacterial properties to DBS carriers.