Chronic disorders of consciousness: role of neuroimaging

3rd International Conference and Young Scientist School "Magnetic resonance imaging in biomedical research"

物理学;医药卫生

Kremneva, E.^1 ; Sergeev, D.^1 ; Zmeykina, E.^1 ; Legostaeva, L.^1 ; Piradov, M.^1

Research Center of Neurology, Moscow, Russia^1

关键词: Chronic disorders;    Cortical network;    Diagnosis and prognosis;    Diagnostic modality;    Neuronal loss;    Structural connectivity;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/886/1/012011/pdf
DOI  :  10.1088/1742-6596/886/1/012011

学科分类：卫生学

来源: IOP

【 摘 要 】

Chronic disorders of consciousness are clinically challenging conditions, and advanced methods of imaging for better understanding of diagnosis and prognosis are needed. Recent functional neuroradiological studies utilizing PET and fMRI demonstrated that besides widespread neuronal loss disruption of interconnection between certain cortical networks after the injury may also play the leading role in the development of behaviourally assessed unresponsiveness. Functional and structural connectivity, evaluated by neuroimaging approaches, may correlate with clinical status and may also play prognostic role. Integration of data from various diagnostic modalities is needed for further progress in this area.