Cerium nanoparticle effect on sensitivity of Fricke gel dosimeter: Initial investigation

9th International Conference on 3D Radiation Dosimetry

Ebenezer Suman Babu, S.^1 ; Timothy Peace Balasingh, S.^1 ; Benedicta Pearlin, R.^1 ; Rabi Raja Singh, I.^1 ; Paul Ravindran, B.^1

Department of Radiotherapy, Christian Medical College, Vellore

632 004, India^1

关键词: Ammonium sulphate;    Cerium oxide nanoparticle;    Distilled water;    Nanoparticle effects;    Optimal concentration;    Oxide nanoparticles;    Radiation sensitivity;    Xylenol Orange;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/847/1/012053/pdf
DOI  :  10.1088/1742-6596/847/1/012053

来源: IOP

【 摘 要 】

Fricke gel dosimeters (FXGs) have been the preferred dosimeters because of its ease in preparation and water and tissue equivalency. Visible changes happen three dimensionally in the dosimeter as the ferrous (Fe2+) ions change into ferric (Fe3+) ions upon irradiation and the measure of this change can be correlated to the dose absorbed. Nanoparticles are promising entities that can improve the sensitivity of the gel dosimeter. Cerium Oxide nanoparticle was investigated for possible enhancement of absorbed dose in the FXG. Various concentrations of the nanoparticle based gel dosimeters were prepared and irradiated for a clinical dose range of 0-3 Gy in a telegamma unit. The optimal concentration of 0.1 mM nanoparticle incorporated in the FXG enhances the radiation sensitivity of the unmodified FXG taken as reference without modifying the background absorbance prior to irradiation. The gel recipe consisted of 5% (wt) gelatin, 50 mM Sulphuric acid, 0.05 mM Xylenol Orange, 0.5 mM Ferrous Ammonium Sulphate and 0.1 mM Cerium (IV) Oxide nanoparticle (