The Potency of White Rice (Oryza sativa), Black Rice (Oryza sativa L. indica), and Red Rice (Oryza nivara) as Antioxidant and Tyrosinase Inhibitor

3rd International Conference on Mathematics, Science and Education 2016

数学;自然科学;教育

Batubara, I.^1,2 ; Maharni, M.^1 ; Sadiah, S.^2,3

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University, Campus IPB Darmaga, Bogor

16680, Indonesia^1

Tropical Biopharmaca Research Center, Bogor Agricultural University, Jalan Taman Kencana No 3, Bogor

16128, Indonesia^2

Department of Anatomy, Physiology and Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Campus IPB Darmaga, 16680, Indonesia^3

关键词: 1 ,1-diphenyl-2-picrylhydrazyl;    Active components;    Anti-oxidant activities;    Different solvents;    Phosphomolybdates;    Radical scavenging;    Tyrosinase inhibition;    Tyrosinase inhibitors;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/824/1/012017/pdf
DOI  :  10.1088/1742-6596/824/1/012017

来源: IOP

【 摘 要 】

Rice is known to have many beneficial biological activities and is often used as "bedak dingin", a face powder. The content of vitamins, minerals, fiber, and several types of antioxidants, such as ferulic acid, phytic acid, tocopherol, and oryzanols [1-2] are predicted to be potential as a tyrosinase inhibitor. The purpose of this study is to determine the potency of extracts from there types of rice, namely white, red, and black rice as an antioxidant and tyrosinase inhibitor. The rice was extracted with three different solvents, n-hexane, ethyl acetate, and methanol. The results showed that the highest antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl method was found in the methanol extract of black rice (IC50290 μg/mL). Meanwhile, ethyl acetate extract of white rice has the highest antioxidant activity withphosphomolybdic acid method (41 mmol α-tocopherol equivalents/g sample). Thus, methanol extract of black rice and ethyl acetate extract of white rice are potential as an antioxidant. For tyrosinase inhibitor, n-hexane extract of red rice (IC503156 μg/mL) was the most active extract. The active component for radical scavenging is polar compound and for antioxidant by phosphomolybdate method is less polar compounds in black rice methanol extract based on TLC bioautogram. In conclusion, the black rice is the most potent in antioxidant while red rice is for tyrosinase inhibition.