Study of iodine, gadolinium and bismuth quantification possibility with micro-CT IVIS spectrumct in vivo imaging system

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Pervova, V.V.^1 ; Lipengolts, A.A.^1,2 ; Cherepanov, A.A.^2 ; Abakumov, M.A.^3

National Research Nuclear University, MEPhI, Russia^1

Blokhin Russian Oncological Scientific Center, Russia^2

Pirogov Russian National Research Medical University, Russia^3

关键词: Absorbed dose;    Contrast-enhanced radiotherapies;    Drug concentration;    Healthy tissues;    In-Vivo imaging;    Minimal damage;    Quantitative determinations;    Water solutions;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012043/pdf
DOI  :  10.1088/1742-6596/784/1/012043

来源: IOP

【 摘 要 】

The main task of radiotherapy is to create prescribed absorbed dose of irradiation in a tumor with minimal damage of healthy tissues. Contrast Enhanced Radiotherapy allows to achieve that by administration of a special drug into the tumor before irradiation, that increases the absorbed dose within the tumor volume. The concentration of the drug determines the value of the absorbed dose, therefore one of the major tasks in CERT is quantification of the drug concentration in the tumor during irradiation procedure. The present work deals with quantitative determination of iodine, gadolinium and bismuth water solutions by use of micro-CT IVIS Spectrum In Vivo Imaging System.