The "PHOENIX" Space Experiment: Study of Space Radiation Impact on Cells Genetic Apparatus on Board the International Space Station

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Karganov, M.Yu.^1,2 ; Alchinova, I.B.^1,2 ; Yakovenko, E.N.^1,2 ; Kushin, V.V.^3,4 ; Inozemtsev, K.O.^3,4 ; Strádi, A.^5 ; Szabó, J.^5 ; Shurshakov, V.A.^4 ; Tolochek, R.V.^4

Research Institute for Space Medicine, Federal Biomedical Agency of Russia, Orekhoviy boulevard, 28, Moscow

115682, Russia^1

Institute of General Pathology and Pathophysiology, Baltiyskaya str., 8, Moscow

125315, Russia^2

National Research Nuclear University, MEPhI (Moscow Engineering Physics Institute), Kashirskoye shosse, 31, Moscow

115409, Russia^3

Russian Academy of Sciences, Institute of Biomedical Problems, Khoroshevskoye shosse, 76A, Moscow

123007, Russia^4

Hungarian Academy of Sciences, Centre for Energy Research (MTA EK), P. O. B. 49, Budapest

H-1525, Hungary^5

关键词: Biological data;    DNA fragmentation;    Human lymphocytes;    International Space stations;    Mouse bone marrow cells;    Space experiments;    Space radiations;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012024/pdf
DOI  :  10.1088/1742-6596/784/1/012024

来源: IOP

【 摘 要 】

The preliminary results of the 1stsession of Russian "PHOENIX" long-term space experiment are presented. The survival of dried human lymphocytes and mouse bone marrow cells in 199 days space flight is studied. The degree of DNA fragmentation is analysed for samples flown in different ISS compartments. It is shown that biological data correlates with the results of space radiation dose measurements.