Multi-scale biomedical systems: measurement challenges

2016 Joint IMEKO TC1-TC7-TC13 Symposium: Metrology Across the Sciences: Wishful Thinking?

Summers, R.^1

Department of Information Engineering, Loughborough University, Loughborough

LE11 3TU, United Kingdom^1

关键词: Biological phenomena;    Biomedical applications;    Biomedical systems;    Epidemiological studies;    Health services;    Holistic perspectives;    New technologies;    Virtual engineering;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/772/1/012014/pdf
DOI  :  10.1088/1742-6596/772/1/012014

来源: IOP

【 摘 要 】

Multi-scale biomedical systems are those that represent interactions in materials, sensors, and systems from a holistic perspective. It is possible to view such multi-scale activity using measurement of spatial scale or time scale, though in this paper only the former is considered. The biomedical application paradigm comprises interactions that range from quantum biological phenomena at scales of 10-12 for one individual to epidemiological studies of disease spread in populations that in a pandemic lead to measurement at a scale of 10+7. It is clear that there are measurement challenges at either end of this spatial scale, but those challenges that relate to the use of new technologies that deal with big data and health service delivery at the point of care are also considered. The measurement challenges lead to the use, in many cases, of model-based measurement and the adoption of virtual engineering. It is these measurement challenges that will be uncovered in this paper.