Ultrashort Phenomena in Biochemistry and Biological Signaling

22nd International Conference on Spectral Line Shapes

Splinter, Robert^1,2

Splinter Consultants, Graham

NC

27253, United States^1

Physics and Optical Science, University of North Carolina at Charlotte, Charlotte

NC

28223, United States^2

关键词: Amplitude and frequency modulations;    Biological phenomena;    Biological signaling;    Chemical interactions;    Depolarization process;    Intercellular communications;    Physiological characteristics;    Ultrashort phenomena;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/548/1/012008/pdf
DOI  :  10.1088/1742-6596/548/1/012008

来源: IOP

【 摘 要 】

In biological phenomena there are indications that within the long pulse-length of the action potential on millisecond scale, there is additional ultrashort perturbation encoding that provides the brain with detailed information about the origin (location) and physiological characteristics. The objective is to identify the mechanism-of-action providing the potential for encoding in biological signal propagation. The actual molecular processes involved in the initiation of the action potential have been identified to be in the femtosecond and pico-second scale. The depolarization process of the cellular membrane itself, leading to the onset of the actionpotential that is transmitted to the brain, however is in the millisecond timeframe. One example of the femtosecond chemical interaction is the photoresponse of bacteriorhodopsin. No clear indication for the spatial encoding has so far been verified. Further research will be required on a cellular signal analysis level to confirm or deny the spatial and physiological encoding in the signal wave-trains of intercellular communications and sensory stimuli. The pathological encoding process for cardiac depolarization is however very pronounced and validated, however this electro-chemical process is in the millisecond amplitude and frequency modulation spectrum.