Budding yeast colony growth study based on circular granular cell

6th Asian Physics Symposium

Aprianti, Devi^1 ; Khotimah, S.N.^2 ; Viridi, S.^2

Computational Science Department, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung

40132, Indonesia^1

Nuclear and Biophysics Research Division, Physics Department, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung

40132, Indonesia^2

关键词: Budding yeasts;    Cell diameters;    Colony formation;    Diameter growth;    Granular cells;    Growth of cells;    Linear correlation;    Specific growth rate;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/739/1/012026/pdf
DOI  :  10.1088/1742-6596/739/1/012026

来源: IOP

【 摘 要 】

Yeast colony growth can be modelled by using circular granular cells, which can grow and produce buds. The bud growth angle can be set to regulate cell budding pattern. Cohesion force, contact force and Stokes force were adopted to accommodate the behaviour and interactions among cells. Simulation steps are divided into two steps, the explicit step is due to cell growing and implicit step for the cell rearrangement. Only in explicit step that time change was performed. In this study, we examine the influence of cell diameter growth time and reproduction time combination toward the growth of cell number and colony formation. We find a commutative relation between the cell diameter growth time and reproduction time to the specific growth rate. The greater value of the multiplication of the parameters, the smaller specific growth rate is obtained. It also shows a linear correlation between the specific growth rate and colony diameter growth rate.