EndoTOFPET-US _ A Miniaturised Calorimeter for Endoscopic Time-of-Flight Positron Emission Tomography

16th International Conference on Calorimetry in High Energy Physics

Zvolský, Milan^1

Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, Hamburg

22607, Germany^1

关键词: Clinical application;    Detector components;    Hardware and software;    Integrated electronics;    Positron emission tomography (PET);    Scintillator crystals;    Silicon photomultiplier;    System integration;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/587/1/012068/pdf
DOI  :  10.1088/1742-6596/587/1/012068

来源: IOP

【 摘 要 】

In the scope of the EndoTOFPET-US project, a novel multimodal device for Ultrasound (US) Endoscopy and Positron Emission Tomography (PET) is being developed. The project aims at detecting and quantifying morphologic and functional markers and developing new biomarkers for pancreas and prostate oncology. Exploiting the Time-of-Flight (TOF) information of the gamma rays allows for a more sensitive, more precise and lower radiation- dose imaging and intervention on small internal structures. The detection of the gamma rays is realised with the help of scintillator crystals with Silicon Photomultiplier (SiPM) read-out, aiming at a coincidence time resolution of 200 ps and a spatial resolution of ≈ 1 mm. For the endoscopic detector, digital SiPMs are utilised for the first time in an instrument planned for clinical applications. The functionality of the instrument as well as the challenges that accompany the high miniaturisation of the endoscopic detector and the asymmetric and variable geometry of the system, are presented. The demands on the system involve the fields of scintillating crystallography, ultra-fast photon detection, highly integrated electronics, system integration as well as image reconstruction. The single detector components have been fully characterised and are performing up to specifications. Two dedicated ASIC chips have been developed for the project. The first PET images have been acquired with a test setup that consists solely of hardware and software developed within the collaboration and demonstrate that the data acquisition and reconstruction chain is operational. In this talk, the characterisation of the single components and the status of the detector integration and comissioning is presented.