In vivo spectroscopy of healthy skin and pathology in terahertz frequency range

International Scientific Seminars on "Fundamental and Applied Problems of Photonics and Condensed Matter Physics"

Zaytsev, Kirill I.^1 ; Kudrin, Konstantin G.^2 ; Reshetov, Igor V.^3 ; Gavdush, Arseniy A.^1 ; Chernomyrdin, Nikita V.^1 ; Karasik, Valeriy E^1 ; Yurchenko, Stanislav O^1

Bauman Moscow State Technical University, 2nd Baumanskaya str. 5, Moscow

105005, Russia^1

P.A.Hertzen Moscow Research Institute of Oncology, 2nd Botkinskiy proezd 3, Moscow

125284, Russia^2

Institute of Improvement of Professional Skill of the Federal Medico-Biological Agency of Russia, Volokolamskoye shosse 91, Moscow

125371, Russia^3

关键词: Basal cell carcinoma;    Biomedical applications;    In-vivo spectroscopy;    Non-invasive diagnosis;    Pulsed spectroscopy;    Scientific community;    Terahertz frequency range;    Terahertz technology;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/584/1/012023/pdf
DOI  :  10.1088/1742-6596/584/1/012023

来源: IOP

【 摘 要 】

Biomedical applications of terahertz (THz) technology and, in particular, THz pulsed spectroscopy have attracted considerable interest in the scientific community. A lot of papers have been dedicated to studying the ability for human disease diagnosis, including the diagnosis of human skin cancers. In this paper we have studied the THz material parameters and THz dielectric properties of human skin and pathology in vivo, and THz pulsed spectroscopy has been utilized for this purpose. We have found a contrast between material parameters of basal cell carcinoma and healthy skin, and we have also compared the THz material parameters of dysplastic and non-dysplastic pigmentary nevi in order to study the ability for early melanoma diagnosis. Significant differences between the THz material parameters of healthy skin and pathology have been detected, thus, THz pulsed spectroscopy promises to be become an effective tool for non-invasive diagnosis of skin neoplasms.