Contrast enhancement of magnetic resonance imaging (MRI) of polymer gel dosimeter by adding Platinum nano- particles

9th National Seminar on Medical Physics

物理学;医药卫生

Deyhimihaghighi, N.^1 ; Noor, N. Mohd^2 ; Soltani, N.^1 ; Jorfi, R.^1 ; Haghir, M Erfani^1 ; Adenan, M.Z.^1 ; Saion, E.^1 ; Khandaker, M.U.^3

Department of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor

43400, Malaysia^1

Department of Imaging, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor

43400, Malaysia^2

Department of Physics, University of Malaya, Kuala Lumpur

50603, Malaysia^3

关键词: Atomic numbers;    Compton effect;    Contrast Enhancement;    Dose enhancements;    Magnetic Resonance Imaging (MRI);    Platinum nano-particles;    Polymer gel dosimeter;    Polymer gels;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/546/1/012013/pdf
DOI  :  10.1088/1742-6596/546/1/012013

学科分类：卫生学

来源: IOP

【 摘 要 】

In this research different concentrations of Platinum nanoparticles (Pt-NPs) embedded in PAGAT polymer gel and irradiated with Cobalt -60 (60Co). The OD of samples indicate significant dose enhancement caused by Pt-NPs. Different concentrations of Pt-NPs were investigated: 0.5×10-2,1×10-22×10-2and 3×10-2mg/l and these were presented the enhancement in OD by the factor of 11.56, 27.10, 15.84 and 10.07 respectively. As the mean energy of60Co is 1.25 MeV and atomic number (Z) of Pt is 78, the predominant effect will be Compton effect and Photoelectric cannot occurred. This work studied the feasibility of using PAGAT polymer gel combined with Pt-NPs as a suitable tool to perform dosimetric investigation of nanoparticles application in radiotherapy as dosimeter and dose enhancer.