Ex vivo Time Evolution of Thrombus Growth through Optical and Electrical Impedance data fusion

2013 Joint IMEKO (International Measurement Confederation) TC1-TC7-TC13 Symposium: Measurement Across Physical and Behavioural Sciences

Affanni, A.^1 ; Specogna, R.^1 ; Trevisan, F.^1

University of Udine, Department of Electrical, Management and Mechanical Engineering, via delle Scienze 206, 33100 Udine, Italy^1

关键词: Electrical impedance;    Flow condition;    Fusion methodology;    Optical imaging;    State of the art;    Time evolutions;    Volume estimations;    Volume growth;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/459/1/012016/pdf
DOI  :  10.1088/1742-6596/459/1/012016

来源: IOP

【 摘 要 】

We designed a novel sensor specifically aimed at ex vivo measurements of white thrombus volume growth; a white thrombus is induced within an artificial micro-channel where hemostasis takes place starting from whole blood under flow conditions. The advantage of the proposed methodology is to identify the time evolution of the thrombus volume by means of an original data fusion methodology based on 2D optical and electrical impedance data simultaneously processed. On the contrary, the present state of the art optical imaging methodologies allow the thrombus volume estimation only at the end of the hemostatic process.