The effect of chemical stability on the NIPAM gel dosimeter using 1H-NMR

7th International Conference on 3D Radiation Dosimetry

Huang, You-Ruei^1 ; Hsieh, Ling-Ling^1 ; Chang, Yuan-Jen^2,3 ; Hsieh, Bor-Tsung^1

Department of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology, Taichung, Taiwan^1

Institute of Biomedical Engineering and Material Science, Central Taiwan University of Science and Technology, Taichung, Taiwan^2

Department of Management Information Systems, Central Taiwan University of Science and Technology, Taichung, Taiwan^3

关键词: Chemical change;    Effect of chemicals;    Gel dosimeter;    N-isopropylacrylamides;    Nipam monomers;    Polymer gel dosimeter;    Polymerization rates;    Radiation-induced;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/444/1/012095/pdf
DOI  :  10.1088/1742-6596/444/1/012095

来源: IOP

【 摘 要 】

Radiation-induced chemical changes in the N-isopropylacrylamide (NIPAM) gels used in three-dimensional dosimeters were investigated using 1H-NMR in this study. The experimental results show that the signal from C=C bonds of NIPAM and N,N'-Methylenediacrylamide (BIS) are 5.5 and 6.3 ppm, respectively. The double bonds from the NIPAM and BIS disappeared with half-dose (D50) were about 10.90 Gy ± 0.76 Gy and 10.09 Gy ± 0.29 Gy, respectively. This observation demonstrates that the polymerization rate of BIS is faster than that of the NIPAM monomer. The 1H-NMR can indicate the chemical structure changes of the polymer gel dosimeter after irradiation and successfully determine the D50 in the NIPAM gel dosimeter.