Dose integration and dose rate characteristics of a NiPAM polymer gel MRI dosimeter system

9th International Conference on 3D Radiation Dosimetry

Waldenberg, C.^1 ; Karlsson Hauer, A.^2,3 ; Gustafsson, C.^3,4 ; Ceberg, S.^3

Department of Radiation Physics, University of Gothenburg, Göteborg, Sweden^1

Department of Therapeutic Radiation Physics, Sahlgrenska University Hospital, Göteborg, Sweden^2

Department of Hematology, Oncology and Radiation Physics, Skane University Hospital, Lund, Sweden^3

Department of Medical Physics, Lund University, Malmö, Sweden^4

关键词: 3d dosimeters;    Beam irradiation;    Dose rate dependence;    Gel dosimeter;    High spatial resolution;    N-isopropylacrylamides;    Normoxic polymer gel;    Statistical significance;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/847/1/012063/pdf
DOI  :  10.1088/1742-6596/847/1/012063

来源: IOP

【 摘 要 】

The normoxic polymer gel dosimeter based on N-isopropyl acrylamide (NiPAM) is a promising full 3D-dosimeter with high spatial resolution and near tissue equivalency. NiPAM gel samples were irradiated to different doses using a linear accelerator. The absorbed dose was evaluated using MRI and statistical significance of the analysed data was calculated. The analysis was carried out using an in-house developed software. It was found that the gel dosimeter responded linearly to the absorbed dose. The gel exhibited a dose rate dependence, as well as a dependence on the sequential beam irradiation scheme. A higher dose rate, as well as a higher dose per sequential beam, resulted in a lower dose response.