How accurate is image guided radiation therapy (IGRT) delivered with a micro-irradiator?

7th International Conference on 3D Radiation Dosimetry

Oldham, M.^1,2 ; Newton, J.^1,2 ; Rankine, L.^1,2 ; Adamovics, J.^3 ; Kirsch, D.^1,2 ; Das, S.^1,2

Department of Radiation Oncology, Durham, NC, United States^1

Duke University Medical Center, Durham, NC, United States^2

Rider University, NJ, United States^3

关键词: Hardware and software;    High resolution;    Image-guided radiation therapy;    Normal tissue damage;    Pre-clinical;    Radiation treatments;    Targeting accuracy;    Tumor control;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/444/1/012070/pdf
DOI  :  10.1088/1742-6596/444/1/012070

来源: IOP

【 摘 要 】

There is significant interest in delivering precisely targeted small-volume radiation treatments, in the pre-clinical setting, to study dose-volume relationships with tumor control and normal tissue damage. In this work we investigate the IGRT targeting accuracy of the XRad225Cx system from Precision x-Ray using high resolution 3D dosimetry techniques. Initial results revealed a significant targeting error of about 2.4mm. This error was reduced to within 0.5mm after the IGRT hardware and software had been recalibrated. The facility for 3D dosimetry was essential to gain a comprehensive understanding of the targeting error in 3D.