A study on the reproducibility and spatial uniformity of N-isopropylacrylamide polymer gel dosimetry using a commercial 10X fast optical-computed tomography scanner

7th International Conference on 3D Radiation Dosimetry

Chang, Y.J.^1,2 ; Lin, J.Q.^1 ; Hsieh, B.T.^3 ; Chen, C.H.^2

Institute of Biomedical Engineering and Material Science, Central Taiwan University of Science and Technology, Taichung, Taiwan^1

Department of Management Information Systems, Central Taiwan University of Science and Technology, Taichung, Taiwan^2

Department of Medical Imaging and Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan^3

关键词: Dose profile;    N- isopropylacrylamide;    N-isopropylacrylamides;    Optical computed tomography;    Polymer gel dosimeter;    Polymer gel dosimetry;    Reproducibilities;    Spatial uniformity;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/444/1/012067/pdf
DOI  :  10.1088/1742-6596/444/1/012067

来源: IOP

【 摘 要 】

This study investigated the reproducibility and spatial uniformity of N-isopropylacrylamide (NIPAM) polymer gel as well as the reproducibility of a NIPAM polymer gel dosimeter. A commercial 10X fast optical computed tomography scanner (OCTOPUS-10X, MGS Research, Inc., Madison, CT, USA) was used as the readout tool of the NIPAM polymer gel dosimeter. A cylindrical NIPAM gel phantom measuring 10 cm (diameter) by 10 cm (height) by 3 mm (thickness) was irradiated by the four-field box treatment with a field size of 3 cm x 3 cm. The dose profiles were found to be consistent at the depths of 2.0 cm to 5.0 cm for two independent gel phantom batches, and the average uncertainty was less than 2%. The gamma pass rates were calculated to be between 94% and 95% at depths of 40 mm for two independent gel phantom batches using 4% dose difference and 4 mm distance-to-agreement criterion. The NIPAM polymer gel dosimeter was highly reproducible and spatially uniform. The results highlighted the potential of the NIPAM polymer gel dosimeter in radiotherapy.