Evaluation of a clinically intuitive quality assurance method

7th International Conference on 3D Radiation Dosimetry

Norris, H.^1 ; Thomas, A.^1 ; Oldham, M.^1

Duke University Medical Center, Durham, NC, United States^1

关键词: Dose-volume histograms;    Dosimetry measurement;    Head and neck imrt;    Highly accurate;    Normal tissue;    Transform methods;    Treatment plans;    Tumor control;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/444/1/012022/pdf
DOI  :  10.1088/1742-6596/444/1/012022

来源: IOP

【 摘 要 】

There is a pressing need for clinically intuitive quality assurance methods that report metrics of relevance to the likely impact on tumor control of normal tissue injury. This paper presents a preliminary investigation into the accuracy of a novel "transform method" which enables a clinically relevant analysis through dose-volume-histograms (DVHs) and dose overlays on the patient's CT data. The transform method was tested by inducing a series of known mechanical and delivery errors onto simulated 3D dosimetry measurements of six different head-and-neck IMRT treatment plans. Accuracy was then examined through the comparison of the transformed patient dose distributions and the known actual patient dose distributions through dose-volume histograms and normalized dose difference analysis. Through these metrics, the transform method was found to be highly accurate in predicting measured patient dose distributions for these types of errors.