A novel dual responsive nanocomposite double network hydrogel with good mechanical property

2018 International Conference of Green Buildings and Environmental Management

土木建筑工程;生态环境科学

Chen, Yang^1 ; Qiao, Shiya^1 ; Yu, Junrong^1 ; Wang, Yan^1 ; Zhu, Jing^1 ; Hu, Zuming^1

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai

201620, China^1

关键词: Breaking strain;    Carboxymethyl chitosan;    Double-network hydrogels;    Drug delivery system;    N- isopropylacrylamide;    PH- and temperature-responsive;    Responsive hydrogels;    Ultra-violet light;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/186/2/012042/pdf
DOI  :  10.1088/1755-1315/186/2/012042

来源: IOP

【 摘 要 】

Mechanical strong intelligent hydrogels have drawn the increasing attention in recent decades. We have designed a novel mechanical strong biocompatible dual pH- and temperature-responsive carboxymethyl chitosan (CMCTs)/graphene oxide (GO)/poly (N-isopropylacrylamide) (PNIPAM) nanocomposite double network hydrogel by a simple, one-pot in situ free radical polymerization initiated by the ultraviolet light, with the GO nanosheets as the crosslink centers instead of toxic common organic crosslinkers. CMCTs, EDC/NHS, or GO nanosheets are the pivotal factors for fabricating the mechanical strong dual responsive hydrogel. By adjusting the above factors, the optimal mechanical strong hydrogel displayed a high compressive strength of 0.792 MPa at the breaking strain of 0.836. Besides, we also investigated the relationship between the swelling and deswelling behaviors of the synthesized hydrogel and the above mentioned factors. Owing to this outstanding performance, they may have the potential application in drug delivery system and chemical valves in the future.