Association between serum concentration of 25-hydroxyvitamin D [25(OH)D] and chronic periodontitis

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Primasari, A.^1 ; Sihombing, K.P.^2

Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, Medan

20136, Indonesia^1

Division of Dental Nurse, Health Polytechnic of Health Ministry of Indonesia Republic, Medan

20137, Indonesia^2

关键词: 25-hydroxyvitamin d;    Animal studies;    Clinical attachments;    Immunomodulatory agents;    Inverse correlation;    Serum concentration;    Spearman correlation;    Tropical climates;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012227/pdf
DOI  :  10.1088/1755-1315/125/1/012227

来源: IOP

【 摘 要 】

Serum concentration of [25(OH)D] in Indonesia is at low level although Indonesia is one of Asia country which has a tropical climate. Vitamin D as an immunomodulatory agent invitro and in animal studies. However, data from clinical studies involvement vitamin D to chronic periodontitis are still controversy. The aim of this study was to evaluate the association between serum concentration of [25(OH)D] and chronic periodontitis. Totally 45 chronic periodontitis patients were analyzed. Spearman correlation models adjusted for subject and parameter included periodontal pocket depth (PPD), clinical attachment loss (CAL), and bleeding on probing (BOP) are analyzed. Totally 51.11% person have serum concentration of [25(OH)D] 21-50ng/mL were called insufficiency, and 15.56% is deficiency. Mean values of PPD >3mm indicating moderate criteria, CAL >4mm meaning severe criteria, and mean grade of BOP >2 degrees means the interdental papilla appears to be filled with little or much blood. Spearman correlation test results showed an inverse correlation between serum concentration of [25(OH)D] to the value of PPD, CAL, and BOP, however, was not statistically significant (r PPD -0.09; r CAL -0.118; r BOP 0.001, p>0.05). Insufficiency serum concentration of 25- hydroxyvitamin D [25(OH)D] was not associated significantly with PPD, CAL, and BOP of chronic periodontitis.