Antimicrobial resistance profile of urinary tract infection at a secondary care hospital in Medan, Indonesia

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Rahimi, A.^1,3 ; Saragih, R.H.^1,4 ; Nainggolan, R.^2,3

Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan

20136, Indonesia^1

Department of Clinical Pathology, Dr. Pirngadi General Hospital, Medan, Indonesia^2

Dr. Pirngadi General Hospital, Medan, Indonesia^3

Haji Adam Malik Central General Hospital, Jalan Bunga Lau No. 17, Medan

20136, Indonesia^4

关键词: Antimicrobial resistances;    Bacterial pathogens;    Etiologic agents;    General hospitals;    High sensitivity;    Low resistance;    Respiratory tract;    Urinary tract infections;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012034/pdf
DOI  :  10.1088/1755-1315/125/1/012034

来源: IOP

【 摘 要 】

Urinary tract infection (UTI) is a considerable health problem which ranks as the second leading cause of infection after respiratory tract one. Antimicrobial resistance in UTI has become a burden in the management of the disease due to high usage of antibiotics. A comprehensive understanding of the etiology and the antimicrobial resistance of the uropathogenic bacteria is essential to provide adequate treatment. This study aims to determine the etiologic agents and their susceptibility pattern in UTI patients. The analysis was performed retrospectively on culture isolates obtained from urine samples received at the Department of Microbiology, Dr.Pirngadi General Hospital, Medan, Indonesia in the period from January 2015 until December 2016. Higher prevalence of UTI was found in female participants of the study in comparison with males. Enterobacter (64.58%) was the most common bacteria revealed as the etiologic agent, followed by E. coli (11.46%), Citrobacter and Klebsiella (9.38% each). Amikacin and meropenem were the most sensitive antimicrobial agents for Enterobacter, E. coli, Citrobacter, and Klebsiella, showing low resistance rate. This study showed that Enterobacter was the most dominant bacterial pathogen of UTI. Amikacin and meropenem were the antibiotics with high sensitivity for UTI treatment.