Lactic Acid Bacteria Producing Inhibitor of Alpha Glucosidase Isolated from Ganyong (Canna Edulis) and Kimpul (Xanthosoma sagittifolium)

International Conference on Natural Products and Bioresource Science 2017

生物科学;化学

Nurhayati, Rifa^1 ; Miftakhussolikhah^1 ; Frediansyah, Andri^1 ; Rachmah, Desy Lailatul^2

Research Unit for Natural Product Technology, Indonesian Institute of Sciences, Jl. Yogya-Wonosari km 31.5, Gading, Playen, Gunungkidul, Yogyakarta, Indonesia^1

Faculty of Biology, Sepuluh November Institute of Technology, Surabaya, Indonesia^2

关键词: Alpha glucosidase;    Canna Edulis;    Glucosidase;    Insulin resistance;    Insulin secretion;    Lactic acid bacteria;    Type-2 diabetes;    Xanthosoma sagittifolium;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/101/1/012009/pdf
DOI  :  10.1088/1755-1315/101/1/012009

学科分类：生物科学（综合）

来源: IOP

【 摘 要 】

Type 2 diabetes is a disease that caused by the failure of insulin secretion by the beta cells of the pancreas and insulin resistance in peripheral levels. One therapy for diabetics is by inhibiting the activity of α-glucosidase. Lactic acid bacteria have the ability to inhibit of α-glucosidase activity. The aims of this research was to isolation and screening of lactic acid bacteria from ganyong tuber (Canna Edulis) and kimpul tuber (Xanthosoma sagittifolium), which has the ability to inhibit the activity of α-glucosidase. Eightteen isolates were identified as lactic acid bacteria and all of them could inhibit the activity of α-glukosidase. The GN 8 isolate was perform the highest inhibition acivity.