Diaquachloro-tris(ethyl-p-Aminobenzoate)copper(II) Chloride: Synthesis, Characterization and In Vitro Investigation of Antibacterial Activity

International Conference on Green and Renewable Energy Resources 2016

能源学;生态环境科学

Rahardjo, S.B.^1 ; Lestari, W.W.^1 ; Syaima, H.^1

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Jl. Ir. Sutami 36 A, Surakarta

57126, Indonesia^1

关键词: Anti-bacterial activity;    Atomic absorption spectroscopy;    Copper chlorides;    Infrared spectrum;    Molar conductivities;    Primary amine groups;    Staphylococcus aureus;    Water molecule;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/75/1/012025/pdf
DOI  :  10.1088/1755-1315/75/1/012025

学科分类：环境科学（综合）

来源: IOP

【 摘 要 】

The new complex of [Cu(benz)3(H2O)2Cl]Cl has been synthesized in 1:4 mole ratio of CuCl2•2H2O and ethyl-p-aminobenzoate (benz) in ethanol at room temperature. The complex was characterized by UV-Vis and infrared spectroscopy, Atomic Absorption Spectroscopy (AAS), thermal analysis, magnetic measurement and molar conductivity. Infrared spectra indicated that benz was coordinated to the metal ion through nitrogen of primary amine group. Water molecules and chloride ion were also coordinated to Cu(II). CuCl2•2H2O, benz, and Cu(II) complex were screened for investigating in vitro antibacterial activity against Staphylococcus aureus and Escherichia coli using a modified Kirby-Bauer method.