Synthesis and Characterization of Composite Hydroxyapatite-Silver Nanoparticles

3rd International Seminar On Sciences "Sciences On Precision And Sustainable Agriculture"

Charlena^1 ; Nuzulia, N.A.^2 ; Handika^1

Department of Chemistry, Bogor Agricultural University, Indonesia^1

Department of Physics, Bogor Agricultural University, Indonesia^2

关键词: Anti-bacterial activity;    Antibacterial properties;    Bacterial infections;    Chemical method;    Hydroxyapatite (HAp);    Infrared spectrum;    Low concentrations;    Synthesis and characterizations;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/58/1/012064/pdf
DOI  :  10.1088/1755-1315/58/1/012064

来源: IOP

【 摘 要 】

Hydroxyapatite (HAp) is commonly used as bone implant coating recently; however, the material has disadvantage such as lack of antibacterial properties, that can cause an bacterial infection. Addition of silver nanoparticles is expected to be able to provide antibacterial properties. Silver nanoparticles was obtained by reduction of AgNO3using glucose monohydrate with microwave heating at 100p for 4 minutes. The composite of hydroxyapatite-silver nanoparticles was synthesized using chemical methods by coprecipitation suspension of Ca(OH)2with (NH4)HPO4, followed by adding silver nanoparticles solution. The size of the synthesized silver nanoparticles was 30-50 nm and exhibited good antibacterial activity. Nevertheless, when it was composited with HAp to form HAp-AgNPs, there was no antibacterial activity due to very low concentration of silver nanoparticles. This was indicated by the absence of silver nanoparticles diffraction patterns. Infrared spectra indicated the presence of chemical shift and the results of scanning electron microscope showed size of the HAp-AgNPs composite was smaller than that of the HAp. This showed the interaction between HAp and the silver nanoparticles.