Screening of Endophytic Fungi from Chlorophyta and Phaeophyta for Antibacterial Activity

Workshop and International Seminar on Science of Complex Natural Systems

Rahaweman, A.C.^1 ; Pamungkas, J.^2 ; Madduppa, H.^3 ; Thoms, C.^3 ; Tarman, K.^1

Department of Aquatic Products Technology, Faculty of Fisheries and Marine Sciences, Bogor Agricultural University, Bogor, West Java

16680, Indonesia^1

Primate Research Center, Faculty of Veterinary Medicine, Bogor Agricultural University, Bogor, West Java

16680, Indonesia^2

Department of Marine Science and Technology, Faculty of Fisheries and Marine Sciences, Bogor Agricultural University, Bogor, West Java

16680, Indonesia^3

关键词: Active metabolites;    Agar diffusion assays;    Anti-bacterial activity;    Endophytic fungi;    Fungal strains;    Macro-algae;    Secondary metabolites;    Staphylococcus aureus;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/31/1/012026/pdf
DOI  :  10.1088/1755-1315/31/1/012026

来源: IOP

【 摘 要 】

Chlorophyta and Phaeophyta macroalgae are important sources of secondary metabolites with pharmaceutically relevant antibacterial, antifungal and antiviral bioactivities. Oftentimes, these algae-derived compounds are, in fact, produced by endophytic fungi living inside the macroalgal tissue. Numerous studies have shown that endophytic fungi can produce a broad range of active metabolites such as terpenes, alkaloids, and quinones. The aim of the present study was to screen fungal strains isolated from a variety of Caulerpa spp., Halimeda spp., and Sargassum spp. for antibacterial activity against Staphylococcus aureus and Escherichia coli. Thirteen morphologically different isolates were tested. Two of them showed pronounced activity against S. aureus in agar diffusion assays.